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  • Power, Sex, Suicide: Mitochondria and the meaning of life

    Power, Sex, Suicide by Lane, Nick;

    Mitochondria and the meaning of life

    Sorozatcím: Oxford Landmark Science;

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    A termék adatai:

    • Kiadás sorszáma 2
    • Kiadó OUP Oxford
    • Megjelenés dátuma 2018. november 1.

    • ISBN 9780198831907
    • Kötéstípus Puhakötés
    • Terjedelem560 oldal
    • Méret 199x158x41 mm
    • Súly 483 g
    • Nyelv angol
    • Illusztrációk 14 line drawings and halftones
    • 30

    Kategóriák

    Rövid leírás:

    Mitochondria are tiny structures within all our cells, believed to have once evolved from bacteria living independent lives. Drawing on cutting edge research, this book explores the fundamental role they play in some of the biggest themes in biology: evolution, the origin of the sexes, in growth, ageing, disease, and in death.

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    Hosszú leírás:

    Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that.

    Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide.

    Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death.

    Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.

    Review from previous edition Challenging, but rewarding.

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    Tartalomjegyzék:

    Introduction: Mitochondria: Clandestine Rulers of the World
    Part 1: Hopeful Monster: The Origin of the Eukaryotic Cell
    The Deepest Evolutionary Chasm
    Quest for a Progenitor
    The Hydrogen Hypothesis
    Part 2: The Vital Force: Proton Power and the Origin of Life
    The Meaning of Respiration
    Proton Power
    The Origin of Life
    Part 3: Insider Deal: The Foundations of Complexity
    Why Bacteria are Simple
    Why Mitochondria Make Complexity Possible
    Part 4: Power Laws: Size and the Ramp of Ascending Complexity
    The Power Laws of Biology
    The Warm-Blooded Revolution
    Part 5: Murder or Suicide: The Troubled Birth of the Individual
    Conflict in the Body
    Foundations of the Individual
    Part 6: Battle of the Sexes: Human Pre-History and the Nature of Gender
    The Asymmetry of Sex
    What Human Prehistory Says About the Sexes
    Why There Are Two Sexes
    Part 7: Clock of Life: Why Mitochondria Kill us in the End
    The Mitochondrial Theory of Ageing
    Demise of the Self-Correcting Machine
    A Cure for Old Age?
    Epilogue
    Glossary
    Further Reading
    Index

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