- Publisher's listprice GBP 13.49
-
6 444 Ft (6 137 Ft + 5% VAT)
The price is estimated because at the time of ordering we do not know what conversion rates will apply to HUF / product currency when the book arrives. In case HUF is weaker, the price increases slightly, in case HUF is stronger, the price goes lower slightly.
- Discount 10% (cc. 644 Ft off)
- Discounted price 5 799 Ft (5 523 Ft + 5% VAT)
Subcribe now and take benefit of a favourable price.
Subscribe
6 444 Ft
Availability
Estimated delivery time: In stock at the publisher, but not at Prospero's office. Delivery time approx. 3-5 weeks.
Not in stock at Prospero.
Why don't you give exact delivery time?
Delivery time is estimated on our previous experiences. We give estimations only, because we order from outside Hungary, and the delivery time mainly depends on how quickly the publisher supplies the book. Faster or slower deliveries both happen, but we do our best to supply as quickly as possible.
Product details:
- Edition number 2
- Publisher OUP Oxford
- Date of Publication 1 November 2018
- ISBN 9780198831907
- Binding Paperback
- No. of pages560 pages
- Size 199x158x41 mm
- Weight 483 g
- Language English
- Illustrations 14 line drawings and halftones 30
Categories
Short description:
Mitochondria are tiny structures within all our cells, believed to have once evolved from bacteria living independent lives. Drawing on cutting edge research, this book explores the fundamental role they play in some of the biggest themes in biology: evolution, the origin of the sexes, in growth, ageing, disease, and in death.
MoreLong description:
Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that.
Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide.
Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death.
Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.
Review from previous edition Challenging, but rewarding.
Table of Contents:
Introduction: Mitochondria: Clandestine Rulers of the World
Part 1: Hopeful Monster: The Origin of the Eukaryotic Cell
The Deepest Evolutionary Chasm
Quest for a Progenitor
The Hydrogen Hypothesis
Part 2: The Vital Force: Proton Power and the Origin of Life
The Meaning of Respiration
Proton Power
The Origin of Life
Part 3: Insider Deal: The Foundations of Complexity
Why Bacteria are Simple
Why Mitochondria Make Complexity Possible
Part 4: Power Laws: Size and the Ramp of Ascending Complexity
The Power Laws of Biology
The Warm-Blooded Revolution
Part 5: Murder or Suicide: The Troubled Birth of the Individual
Conflict in the Body
Foundations of the Individual
Part 6: Battle of the Sexes: Human Pre-History and the Nature of Gender
The Asymmetry of Sex
What Human Prehistory Says About the Sexes
Why There Are Two Sexes
Part 7: Clock of Life: Why Mitochondria Kill us in the End
The Mitochondrial Theory of Ageing
Demise of the Self-Correcting Machine
A Cure for Old Age?
Epilogue
Glossary
Further Reading
Index
Religion und Geschichte im evangelischen Christentum.: Olaus-Petri-Vorlesungen, gehalten an der Universität Uppsala.
7 382 HUF
7 013 HUF
