Post-transcriptional Gene Regulation in Human Disease by Prakash Jain, Buddhi; K Goswami, Shyamal; Sharma, Tapan;

Sorozatcím: Translational Epigenetics; 32;

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A termék adatai:

Kiadó Elsevier Science
Megjelenés dátuma 2022. augusztus 16.

ISBN 9780323913058
Kötéstípus Puhakötés
Terjedelem394 oldal
Méret 234x190 mm
Súly 810 g
Nyelv angol
Illusztrációk 70 illustrations (30 in full color)

Kategóriák

Genetika, evolúció, fejlődéstan Molekuláris biológia Genetika Genetika, evolúció, fejlődéstan (karitatív célú kampány) Molekuláris biológia (karitatív célú kampány) Genetika (karitatív célú kampány)

Hosszú leírás:

Post-transcriptional Gene Regulation in Human Disease, a new volume in the Translational Epigenetics book series, offers a thorough overview and discussion of post-transcriptional genetic control mechanisms and their roles across various pathologies and human developmental outcomes, along with regulatory mechanisms targeted for therapeutic approaches. The book is broadly divided in two parts: early chapters describe the basics of post-transcriptional gene regulation, associated epigenetic mechanisms, the role of RNA binding proteins, the evolution of post-transcriptional gene regulation, and methods to study these mechanisms. The second half of the book includes deeper discussion of post-transcriptional gene regulation across specific diseases and therapeutics targets. Various post-transcriptional events, including alternative splicing and polyadenylation, mRNA stability, and miRNAs and their involvement in the disease progression, are examined in detail.

Több

Tartalomjegyzék:

1. Regulation of Gene Expression in Mammals: An Overview
2. Post Transcriptional Gene Regulation: An Overview
3. Methods to Study Post-Transcriptional Regulation of Gene Expression
4. Epigenetic Regulation of Post-Transcriptional Machinery
5. Post-Transcriptional Regulation: A Less Explored Territory in the World of Neurodegenerative Diseases
6. Role of Post-Transcriptional Gene Regulation in Hematological Malignancies
7. Post-Transcriptional Gene Regulation in Solid Tumors
8. A Comprehensive View of the Prostate Cancer Metastasis and Role of Androgen Receptor Splice Variants
9. Post-Transcriptional Gene Regulation in Cardiorenal Syndrome
10. Noncoding RNAs as Modulators of Post-Transcriptional Changes and Their Role in CVDs
11. microRNAs as Critical Regulators in Heart Development and Diseases
12. MicroRNA Regulation in Autoimmune Diseases
13. Post-Transcriptional Regulation of Inflammatory Disorder
14. Post-Transcriptional Gene Regulation in Metabolic Syndrome
15. Post-Transcriptional Regulation of HIV-1 Gene Expression: Role of Viral and Host Factors
16. Post-Transcriptional Regulation of Gene Expression in Entamoeba histolytica
17. Post-Transcriptional Regulation of Gene Expression in the Human Malaria Parasite Plasmodium falciparum
18. Hepcidin-Induced Degradation of Iron Exporter Ferroportin Determines Anemia of Chronic Diseases
19. Post-Transcriptional Regulation of Genes and Mitochondrial Disorder