Pharmaceutical Dosage Forms and Drug Delivery by Mahato, Ram I.; Narang, Ajit S.; Kumar, Virender;

Rövid leírás:

Completely revised and updated, this fourth edition elucidates the principles of pharmaceutics, biopharmaceutics, dosage form design, and drug delivery – including emerging new biotechnology-based treatment modalities. The authors integrate aspects of physical pharmacy, chemistry, biology, and biopharmaceutics into drug delivery.

Hosszú leírás:

Completely revised and updated, this fourth edition elucidates the principles of pharmaceutics, biopharmaceutics, dosage form design, and drug delivery – including emerging new biotechnology-based treatment modalities. The authors integrate aspects of physical pharmacy, chemistry, biology, and biopharmaceutics into drug delivery.

With the expiration of older patents and generic competition, the biopharmaceutical industry is evolving faster than ever. Consequently, this edition of the book emphasizes the heightened focus that the recent remarkable progress in gene editing, immunotherapy, and nanotechnology has brought to the design of new drugs and diagnostic approaches along with novel dosage forms.

Apart from new chapters, this edition highlights the emerging emphasis on the role of artificial intelligence (AI) in drug discovery, mRNA and antibody-based therapies, genome editing, immunotherapy, chemical kinetics, and the stability of drug products.

Features:

·         Includes new chapters on antibody therapeutics, gene editing, and immunotherapy.

·         Explains newer approaches and future methods and the significance of artificial intelligence (AI) in drug discovery. 

·         Updated sections on pharmacy mathematics, chemical kinetics, and the stability of medicinal products. 

·         Important updates on parenteral drug products, protein and peptide treatments, and biotechnology-based pharmaceuticals to provide a contemporary perspective on drug development, delivery, and pharmaceutical sciences.

·         Expansion of review questions and answers to clarify concepts for students and add to their grasp of key concepts covered in this book.

Although there are numerous books on pharmaceutics and dosage forms, most cover different areas of the discipline and do not provide an integrated approach. The integrated approach of this book not only provides a singular perspective of the overall field, but also supplies a unified source of information for students, instructors, and professionals, saving their time and money.

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Tartalomjegyzék:

Section I. Introduction

1.             Drug discovery

2.             Drug Development

3.             Pharmaceutical Considerations

4.             Biopharmaceutical Considerations

5.             Pharmacy Math and Statistics

Section II. Physicochemical Principles

6.             Complexation and Protein Binding

7.             Chemical Kinetics and Stability

8.             Interfacial Phenomena

9.             Colloidal Dispersion

10.          Surfactants and Micelles

11.          Pharmaceutical Polymers

12.          Rheology

13.          Radiopharmaceuticals

14.          Drug Delivery Systems

15.          Organ-specific drug delivery

Section III. Dosage Forms

16.          Suspensions

17.          Emulsions

18.          Pharmaceutical Solutions

19.          Powders and Granules

20.          Tablets

21.          Capsules

22.          Parenteral Dosage Forms

23.          Semisolid Dosage Forms

24.          Inserts, Implants, and Devices

Section IV.  Pharmaceutical Biotechnology

25. Protein- and Peptide-Based Dosage Forms

26. Antibody Therapeutics

27. Biotechnology-Based Dosage Forms

28. Genome editing technologies

29. Immunotherapy

30.          Answers

31.          Index