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  • Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas: Molecular Genetics: Liver and Pancreatic Carcinomas V3

    Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas by Hayat, M. A.;

    Molecular Genetics: Liver and Pancreatic Carcinomas V3

    Sorozatcím: Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas;

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    A termék adatai:

    • Kiadó Elsevier Science
    • Megjelenés dátuma 2005. szeptember 21.

    • ISBN 9780120884049
    • Kötéstípus Keménykötés
    • Terjedelem432 oldal
    • Méret 279x215 mm
    • Súly 1840 g
    • Nyelv angol
    • 0

    Kategóriák

    Hosszú leírás:

    Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today.

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    Tartalomjegyzék:

    Chapter 1: Quality Assurance in Immunohistochemistry

    Chapter 2: Methodology of Microarray Data Analysis

    Chapter 3: Microarray-Based Gene Expression Analysis of Defined Tumor Areas

    Chapter 4: Tissue Microarray and Quantitative Fluorescence Image Analysis in Tumor Biomarker Analysis

    Chapter 5: Identification of Differentially Expressed Genes Using Rapid Subtraction Hybridization: Detailed Methodology for Performing Rapid Subtraction Hybridization

    Chapter 6: Noncontact Laser Microdissection and Pressure Catapulting: A Basic Tool in Genomics, Transcriptomics, and Proteomics

    Chapter 7: DNA Methylation Analysis of Human Cancer

    Chapter 8: Antiepidermal Growth Factor Receptor Antibody: Immunohistochemistry

    Chapter 9: PTEN and Cancer

    Chapter 10: The Role of p53 and p73 Genes in Tumor Formation

    Chapter 11: Analysis of Centrosome Amplification in Cancer

    Chapter 1: Liver Carcinoma

    Chapter 2: Mechanisms of Human Hepatocarcinogenesis: An Overview

    Chapter 3: Genes Involved in Hepatocellular Carcinoma

    Chapter 4: Role of p53 and ZBP-89 in Hepatocellular Carcinoma

    Chapter 5: Role of Immunohistochemical Expression of PTEN in Hepatocellular Carcinoma

    Chapter 6: The Potential Role of Bcl-2 and Protein Expression in Hepatocellular Carcinomas: A Clinicopathologic Study

    Chapter 7: The Detection and Clinical Aspect of Immunohistochemical Analysis of Bcl-xL Protein in Hepatocellular Carcinoma

    Chapter 8: Growth Arrest DNA Damage-Inducible Gene 45 ? in Human Hepatocellular Carcinoma

    Chapter 9: Immunohistochemical Detection of DNA Topoisomerase II? in Hepatocellular Carcinoma

    Chapter 10: Role of Immunohistochemical Expression of DNA Methyltransferases in Hepatocellular Carcinoma

    Chapter 11: Role of Hepatitis B Surface Antigen in Hepatocarcinogenesis

    Chapter 12: Immunohistochemical Detection of Host Gene Products Up-Regulated by Hepatitis B Virus X Antigen and Their Putative Roles in Hepatocellular Carcinoma

    Chapter 13: Distinction between Well-Differentiated Hepatocellular Carcinoma and Benign Hepatocellular Nodular Lesions, Using Fine-Needle Aspiration Biopsy

    Chapter 14: Immunohistochemical Detection of EBAG9/RCAS1 Expression in Hepatocellular Carcinoma

    Chapter 15: Hepatocellular Carcinoma of Differential Viral Origin: Analysis by Oligonucleotide Microarray

    Chapter 1: Pancreatic Carcinoma: An Introduction

    Chapter 2: Detection of Genomic Imbalances in Endocrine Pancreatic Tumors Using Comparative Genomic Hybridization

    Chapter 3: Molecular Detection of Micrometastases in Pancreatic Cancer

    Chapter 4: K-ras Protooncogene in Human Pancreatic Cancer

    Chapter 5: Altered Expression of p27 Protein in Pancreatic Carcinoma

    Chapter 6: The Role of DUSP6/MKP-3 in Pancreatic Carcinoma

    Chapter 7: Expression of Carbohydrate Antigens in Pancreatic Cancer

    Chapter 8: Role of Mucins in Pancreatic Carcinoma

    Chapter 9: Immunohistochemical Detection of Cyclooxygenase-2 in Pancreatic Ductal Adenocarcinomas and Neuroendocrine Tumors

    Chapter 10: Immunohistochemical Detection of Activated Stat3 Protein in Pancreatic Cancer

    Chapter 11: The Role of Transcription Factor E2F-1 in Pancreatic Ductal

    Chapter 12: Role of Immunohistochemical Expression of Chromogranins in Pancreatic Endocrine Tumors

    Chapter 13: Role of Immunohistochemical Expression of Maspin in Pancreatic Carcinoma

    Chapter 14: Role of Mast Cells in Pancreatic Carcinoma

    Chapter 15: Endocrine Cells in Invasive Ductal Adenocarcinoma of the Pancreas: An Immunohistochemical Study

    Chapter 16: Fine-Needle Aspiration Biopsy of Pancreatic Adenocarcinoma

    Chapter 17: Immunohistochemical Expression of Mitogen-Activated Protein Kinase Kinase 2 in Pancreatic Cancer

    Index

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