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  • Wills' Biochemical Basis of Medicine, 3Ed

    Wills' Biochemical Basis of Medicine, 3Ed by Wills, Eric; Papachristodoulou, Despo; Thomas, Hywel;

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      • Kiadói listaár GBP 58.99
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        28 182 Ft (26 840 Ft + 5% áfa)
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    28 182 Ft

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    A beszerzés időigényét az eddigi tapasztalatokra alapozva adjuk meg. Azért becsült, mert a terméket külföldről hozzuk be, így a kiadó kiszolgálásának pillanatnyi gyorsaságától is függ. A megadottnál gyorsabb és lassabb szállítás is elképzelhető, de mindent megteszünk, hogy Ön a lehető leghamarabb jusson hozzá a termékhez.

    A termék adatai:

    • Kiadás sorszáma 3, New edition
    • Kiadó CRC Press
    • Megjelenés dátuma 1997. április 10.

    • ISBN 9780750620130
    • Kötéstípus Puhakötés
    • Terjedelem496 oldal
    • Méret 266x202x32 mm
    • Súly 1226 g
    • Nyelv angol
    • Illusztrációk 430 b/w illus
    • 0

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    Hosszú leírás:

    Will's Biochemical Basis of Medicine provides a core of biochemical knowledge, integrating major trends in biochemistry into a comprehensive understanding of biological systems.



    In this new edition the authors have substantially rewritten text and added new chapters on recombinant DNA and genetic engineering, free radicals in health and disease, metabolism in injury and trauma, diabetes mellitus and amyotrophic lateral sclerosis.



    A thorough understanding of biochemistry is increasingly important to the practice of clinical medicine. This comprehensive text sets biochemistry in context for students in basic medical and dental sciences, clinical sciences and allied health sciences.

    In the preface to this edition, the authors summarise the aims of the original author - Professor Eric D. Wills - in preparing such a text. They were to 'present those biochemical principles that are fundamental to the study of medicine; to relate biochemistry to other basic medical sciences such as histology, physiology and pharmacology; to discuss in biochemical terms, studies on the structure of organelles, cells, tissues and the whole body; and to apply this knowledge to an understanding of health maintenance and of disease processes. To this end, the book consists of 43 chapters divided into five main sections: Cellular and Molecular Biology; Human metabolism and nutrition; Specialised metabolism of tissues; Health, disease and the environment; and a Biochemical perspective on disease and its treatment. The first section examines in quite some depth (for undergraduate medical students) the various intracellular structures and their relationship to the body as a whole. In this section, I found the authors' treatment of the modes and importance of biochemical communication occuring between the functionally different cells quite enlightening... classified as 'spatial' (e.g. for organisation of cells into tissues) and 'temporal' (e.g. targeted cells information of when and for (how) long to alter their chemistry)

    ... To complete the picture, the contribution of each of the food groups as a whole to maintenance of the metabolic equilibrium, as well as the effect of a prolonged surplus or deficit of any of these nutrient groups have on the preservation of this state is examined. To consolidate this section for future clinicians, the author describes the assessment of nutritional status, the classification and measurement of obesity, and also mentions the effects of toxicity due to food additives and contaminants. Part three of the book examines specialised metabolism of specific tissues - blood (its intracellular metabolism and the coagulation mechanism), liver, kidney, muscle, endocrine tissues, bone, brain, eye and the immune system. He describes the differing metabolic roles played by this diversity of cell types, as well as targeting specific metabolic dysfunctions involving them. In the fourth section, the positive and negative effects of the environment on the health of the body are examined. He defines these environmental challenges broadly as free radicals and toxic substances (both organic and metallic). After examining the toxicity of some specific substances, the author first considers the metabolic processes available to the body to dispose of foreign compounds, then devotes a chapter to the consideration of cancer formation in the body as a result of multiple environmental challenges. Here, he reminds his readers of the interrelated contributions of the environment (toxins

    The stated goal of the final section is to encourage the readers to develop a biochemical perspective on the development and treatment of disease. He introduces the techniques and applications of recombinant DNA and genetic engineering, as well as the spectrum of chemotherapy (antibiosis and cancer treatment), in each case, endeavoring to relate their activity to the molecular or cellular level. I found the next chapter fascinating, as it describes the role of metabolism to the phases of trauma and injury (ebb/shock phase, flow/catabolic phase, and the convalescent/anabolic phase). The author seeks to make the point that in their treatment of trauma victims, his readers will perform their task more effectively by appropriately modifying their management of the patient through consideration of these three altered metabolic states. Finally, three conditions - diabetes mellitus, asthma and amyotrophic lateral sclerosis (motor neuron disease) - are examined in some detail; considering possible causes, their deleterious effects on the body's metabolism, and the metabolic effects (and side-effects!) of some agents used to treat these conditions. The book is well supplied with clearly annotated diagrams and the occasional photograph. ... it is bountifully filled throughout, with the useful information collected into tables and diagrams set in their respective sections. The text I found to be distinctly authoritative as well as clear and informative. ... this text can place in contex
    Mr. P. Allan, Supervising Scientist, Queensland He

    Will's Biochemical Basis of Medicine provides a core of biochemical knowledge, integrating major trends in biochemistry into a comprehensive understanding of biological systems.



    In this new edition the authors have substantially rewritten text and added new chapters on recombinant DNA and genetic engineering, free radicals in health and disease, metabolism in injury and trauma, diabetes mellitus and amyotrophic lateral sclerosis.



    A thorough understanding of biochemistry is increasingly important to the practice of clinical medicine. This comprehensive text sets biochemistry in context for students in basic medical and dental sciences, clinical sciences and allied health sciences.

    Több

    Tartalomjegyzék:

    Part 1 Cellular and Molecular Biology
    What happens where in the living mammalian cell
    Roles of extracellular and intracellular membranes: membrane structure and membrane transport
    Biochemical communication
    Cellular organelles: the nucleus
    Cellular organelles: mitochondria and energy conservation
    The cytosol
    Cellular organelles: the endoplasmic reticulum and Golgi apparatus
    Cellular organelles: lysosomes
    Part 2 Human Metabolism and Nutrition
    Plasma glucose and its regulation
    Plasma lipids and their regulation
    Plasma amino acids and utilisation of amino acids by tissues
    Plasma calcium and phosphate
    Digestion and absorption of foodstuffs
    Nutrition: general aspects
    Nutrition: energy
    Nutrition: proteins
    Nutrition: lipids and carbohydrates
    Nutrition: obesity and starvation
    Nutrition: vitamins
    Nutrition: inorganic constituents in the diet
    Nutrition: iron and iron metabolism
    Nutrition: folate and vitamin B12.
    Part 3 Specialised Metabolism of Tissues: Blood: metabolism in the red blood cell
    Blood blood clotting
    The liver
    The kidney
    Muscle
    The endocrine tissues
    Bone
    The brain
    The eye
    The immune system
    Part 4 Health, Disease and the Environment: Free radicals in health and disease
    Toxicology: general principles
    Toxic metals
    Metabolism of foreign compounds
    Multiple environmental challenges: cancer. Part 5: A Biochemical Perspective on Disease and its Treatment
    Recombinant DNA and genetic engineering
    Biochemical principles of chemotherapy and drug resistance
    Metabolism in injury and trauma
    Diabetes mellitus
    Asthma
    Amyotrophic lateral sclerosis.

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