Handbook of Nuclear Medicine and Molecular Imaging for Physicists - Three Volume Set by Ljungberg, Michael;

Rövid leírás:

This state-of-the-art handbook provides medical physicists with a comprehensive overview of the field of nuclear medicine.

Hosszú leírás:

This state-of-the-art set of handbooks provides medical physicists with a comprehensive overview of the field of nuclear medicine. In addition to describing the underlying, fundamental theories of the field, it includes the latest research and explores the practical procedures, equipment, and regulations that are shaping the field and it's future. This set is split into three volumes, respectively titled: Instrumentation and Imaging Procedures; Modelling, Dosimetry and Radiation Protection; and Radiopharmaceuticals and Clinical Applications.

Volume one, Instrumentation and Imaging Procedures, focuses primarily on providing a comprehensive review into the detection of radiation, beginning with an introduction to the history of nuclear medicine to the latest imaging technology. Volume two, Modelling, Dosimetry and Radiation Protection, explores the applications of mathematical modelling, dosimetry, and radiation protection in nuclear medicine. The third and final volume, Radiopharmaceuticals and Clinical Applications, highlights the production and application of radiopharmaceuticals and their role in clinical nuclear medicine practice.

These books will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine.

• The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine








• Edited by a leader in the field, with contributions from a team of experienced medical physicists, chemists, engineers, scientists, and clinical medical personnel








• Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history

"This is a high quality, three volume set, bound in striking glossy red and black. The formatting is clear and the text printed in dark grey ink, an unusual choice that nevertheless makes the dense pages of text, formulae, grey and white diagrams and photographs an easier read during prolonged study. Edited by professor of medical radiation physics Michael Ljungberg from Lund University, a renowned authority on Monte Carlo modelling, it includes contributions from medical physicists who will be familiar names to many in the UK community. The content is predominantly written from a European perspective, although a chapter on the IAEA is included to provide some broader international context.

Volume I covers instrumentation and imaging procedures. This wideranging volume opens with a brief history of nuclear medicine before moving on to discuss radiation and detector physics, and the details of gamma cameras, PET, CT, MR and hybrid systems, as well as more niche imaging technologies. There are shorter chapters on acquisition protocols for clinical imaging, providing examples of how this knowledge is applied in practice. Volume II covers modelling, dosimetry and radiation protection. This volume provides the reader with a grounding in biostatistics, radiobiology, kinetic analysis and radiation protection, before a detailed and focused discussion of the application of these principles in dosimetry and radiation safety. Volume III covers radiopharmaceuticals and clinical applications. It begins with an overview of the principles behind radiopharmacy before moving on to the details of radiopharmaceuticals, all aspects of their production, and both clinical and research applications…The set covers a wide range of relevant material…each chapter stands on its own merits and provides valuable, in-depth information from subject experts…Ljundberg’s trilogy would make an excellent addition to any nuclear medicine department library."
— Dr Heather Williams, consultant medical physicist, The Christie NHS Foundation Trust, Manchester in RAD Magazine, May, 2023

Tartalomjegyzék:

Volume I: Instrumentation and Images Processing.

1.  The History of Nuclear Medicine

2.  Basics of Nuclear Physics

3.  Basics of Radiation Interaction in Matter

4.  Radionuclide Production

5.  Radiometry

6.  Scintillation Detectors

7.  Semiconductor Detectors

8.  Gamma Spectroscopy

9.  Properties of the Digital Image

10.  Digital Image Processing

11.  Machine-Learning

12.  Image File Structures in Nuclear Medicine

13.  The Scintillation Camera 

14.  Collimators for Gamma Ray Imaging

15.  Image Acquisition Protocols

16.  Single Photon Emission Computed Tomography (SPECT) and SPECT/CT Hybrid Imaging

17.  Dedicated Tomographic Single Photon Systems

18.  Positron Emission Tomography (PET)

19.  Dead Time Effects in Nuclear Medicine Imaging Studies

20.  Principles of Iterative Reconstruction for Emission Tomography

21.  Clinical Molecular PET/CT Hybrid Imaging

22.  Clinical Molecular PET/MRI Hybrid Imaging

23.  Quality Assurance of Nuclear Medicine Systems

24.  Calibration and Traceability

25.  Activity Quantification from Planar images

26.  Quantitation in Emission Tomography

27.  Multicenter studies: Hardware and Software Requirements

28.  Pre-Clinical Molecular Imaging Systems

29.  Monte Carlo simulations of Nuclear Medicine Imaging Systems

30.  Beta and Alpha Particle Autoradiography

31.  Principles behind Computed Tomography (CT)

32.  Principles behind Magnetic Resonance Imaging (MRI)

Volume II: Dosimetry and Radiation Protection .

1.  Introduction to Biostatistics

2.  Radiobiology

3.  Diagnostic Dosimetry

4.  Time-Activity Curves: Data, Models, Curve Fitting and Model Selection

5.  Tracer Kinetic Modelling and its use in PET Quantification

6.  Principles of Radiological Protection in Healthcare

7.  Controversies in Nuclear Medicine Dosimetry

8.  Monte Carlo Simulation of Photon and Electron Transport in Matter

9.  Patient Models for Dosimetry Applications

10.  Patient-Specific Dosimetry Calculations

11.  Whole Body Dosimetry

12.  Personalized Dosimetry in Radioembolization

13.  Thyroid Imaging and Dosimetry

14.  Bone Marrow Dosimetry

15.  Cellular and Multicellular Dosimetry

16.  Alpha-Particle Dosimetry

17.  Staff Radiation Protection

18.  IAEA support to Nuclear Medicine

 Volume III: Radiopharmaceuticals and Clinical Applications.

1.  Principles behind Radiopharmacy

2.  Radiopharmaceuticals for diagnostics: Planar/SPECT

3.  Radiopharmaceuticals for diagnostics: PET

4.  Radiopharmaceuticals for radionuclide therapy

5.  Design Considerations for a Radiopharmaceutical Production Facility

6.  Methods and Equipment for Quality Control of Radiopharmaceuticals

7.  Environmental Compliance and Control for Radiopharmaceutical Production: Commercial Manufacturing and Extemporaneous Preparation

8.  GMP - rules and recommendations

9.  Management of Radioactive Waste in Nuclear Medicine

10.  Translation of Radiopharmaceuticals: Mouse to Man

11.  Radionuclide Bone Scintigraphy

12.  Radionuclide Examinations of the Kidneys

13.  Neuroimaging in Nuclear Medicine

14.  Methodology and Clinical Implementation of Ventilation/Perfusion Tomography for Diagnosis and Follow-up of Pulmonary Embolism and Other Pulmonary Diseases Clinical use of hybrid V/P SPECT-CT

15.  Myocardiac Perfusion Imaging

16.  Infection and Inflammation

17.  Special Considerations In Pediatric Nuclear Medicine

19.  Antibody-Based Radionuclide Imaging

18.  Radionuclide-Based Diagnosis and Therapy of Prostate Cancer

20.  Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors

21.  Lymphoscintigraphy

22.  Diagnostic Ultrasound
Tomas Jansson

23.  Clinical Trials - Purpose and Procedures

24.  Introduction to Patient Safety and Improvement Knowledge

25.  Closing remarks