Duchenne Muscular Dystrophy
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10% KEDVEZMÉNY?
- A kedvezmény csak az 'Értesítés a kedvenc témákról' hírlevelünk címzettjeinek rendeléseire érvényes.
- Kiadói listaár GBP 192.50
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86 913 Ft (82 775 Ft + 5% áfa)
Az ár azért becsült, mert a rendelés pillanatában nem lehet pontosan tudni, hogy a beérkezéskor milyen lesz a forint árfolyama az adott termék eredeti devizájához képest. Ha a forint romlana, kissé többet, ha javulna, kissé kevesebbet kell majd fizetnie.
- Kedvezmény(ek) 10% (cc. 8 691 Ft off)
- Kedvezményes ár 78 222 Ft (74 498 Ft + 5% áfa)
Iratkozzon fel most és részesüljön kedvezőbb árainkból!
Feliratkozom
86 913 Ft
Beszerezhetőség
Bizonytalan a beszerezhetőség. Érdemes még egyszer keresni szerzővel és címmel. Ha nem talál másik, kapható kiadást, forduljon ügyfélszolgálatunkhoz!
Why don't you give exact delivery time?
A beszerzés időigényét az eddigi tapasztalatokra alapozva adjuk meg. Azért becsült, mert a terméket külföldről hozzuk be, így a kiadó kiszolgálásának pillanatnyi gyorsaságától is függ. A megadottnál gyorsabb és lassabb szállítás is elképzelhető, de mindent megteszünk, hogy Ön a lehető leghamarabb jusson hozzá a termékhez.
A termék adatai:
- Kiadás sorszáma 3
- Kiadó OUP Oxford
- Megjelenés dátuma 2003. szeptember 4.
- ISBN 9780198515319
- Kötéstípus Keménykötés
- Terjedelem282 oldal
- Méret 240x161x19 mm
- Súly 615 g
- Nyelv angol
- Illusztrációk numerous halftones and line drawings 0
Kategóriák
Rövid leírás:
In this third edition of the classic monograph on Duchenne Muscular Dystrophy, Alan Emery is joined by Francesco Muntoni to provide an update on the molecular basis of the disorder, the implications for genetic counselling and prenatal diagnosis, as well as advances in the care of affected children and new possibilities in gene therapy.
TöbbHosszú leírás:
Duchenne Muscular Dystrophy, an inherited and progressive muscle wasting disease, is one of the most common single gene disorders found in the developed world.
In this third edition of the classic monograph on the topic, Alan Emery is joined by Francesco Muntoni, Professor of Paediatric Neurology, to provide a thorough update on all aspects of the disorder.
Identification of the genetic defect responsible for Duchenne Muscular Dystrophy and isolation of the protein dystrophin have led to the development of new theories for the disease's pathogenesis. This new edition incorporates these advances from the field of molecular biology, and describes the resultant opportunities for screening, prenatal diagnosis, genetic counselling and management. Although there is still no cure for the disorder, there have been significant developments in
understanding the progression of the disease, and advances in the management of respiratory and cardiac complications. Emery and Muntoni also explore and speculate on the possibilities for future treatments employing drugs and gene therapies.
This book will appeal not only to scientists and clinicians, but also to a wide range of therapists and other professionals involved in the care of patients with muscular dystrophy.
Over the past 20 years or so Alan E.H. Emery's monograph has been an indispensable introduction into the theme for the novice and a reliable reference book for the expert . . . the third edition . . . clearly benefits from the complementing expertise of its authors - a medical geneticist who has witnessed most of the clinical improvements and all of the basic molecular findings of the past decades and a child neurologist who runs one of the largest neuro-paediatric units in Europe.
The historical attempts to understand this complex disease are well-presented and set the stage for our current - still fragmentary - understanding. This is complemented with clinical data from own observation and with paradigmatic photographs.
The book can be highly recommended further on as a comprehensive introduction to every clinician who is confronted with muscular dystrophy patients and any geneticist who wants to study one of the most multifarious genetic disorders.
Tartalomjegyzék:
Introduction
History of the disease
Clinical features
Confirmation of the diagnosis
Differential diagnosis
Involvement of tissues other than skeletal muscle
Biochemistry of Duchenne muscular dystrophy
Genetics
Molecular pathology
Pathogenesis
Prevention
Genetic counselling
Management
Appendices
A Duchenne's obituary
B MRC grading of muscle strength
C Swinyard grade
D Vignos grade
E Hammersmith motor ability score
F Clinical investigation of Duchenne dystrophy (CIDD) group
G Polymorphisms in the dystrophin gene
H Muscular dystrophy associations and groups in various countries
