Toxin
The cunning of bacterial poisons
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Product details:
- Publisher OUP Oxford
- Date of Publication 27 October 2005
- ISBN 9780198605584
- Binding Hardback
- No. of pages204 pages
- Size 224x147x21 mm
- Weight 378 g
- Language English
- Illustrations numerous halftones, 1 table, 1 line drawing 0
Categories
Short description:
Alistair Lax takes a fascinating look at these most devious molecules, explaining the many ingenious mechanisms they use to penetrate our cell's defences, and the deadly pandemics that result. A story not only of disease but also of human rivalry and persistence in our struggle to understand, combat, and harness these powerful toxins.
MoreLong description:
What do the following have in common: the promise of Botox as the key to everlasting youthful looks; E. coli O157 hamburger disease; a mysterious illness which killed 35 heroin users in 2000; and the assassination by poisoned umbrella-tip of a Bulgarian dissident in the 1970s? The answer is that all of these are caused by toxins, the powerful biological poisons released by bacteria and some plants.
In Toxin, Alistair Lax reveals the panoply of ways in which bacterial toxins overcome the defences of our cells. He explains how they work, how they are so successful in causing major diseases, the terrible human impact they have had, and how apparently 'new' diseases arise from them. He also discusses how we can combat toxins, and how we can harness their actions for beneficial purposes. Enlivened by the very human story of the persistence, rivalries, and insights from which modern microbiology grew, Toxin is the first widely accessible account of this exciting and important topic.
An enjoyable read. I would thoroughly recommend Toxin to students of biology and related subjects.
Table of Contents:
Toxins are everywhere: how toxins affected history
The germ of an idea: a gradual acceleration up to the mid 1850s
The Golden Age of Microbiology: Pasteur, Koch and the birth of the toxin concept
The anatomy of diphtheria: taming the deadly scourge of childhood
Understanding: all toxins fit into three basic mechanisms
Why are plague and typhoid so deadly? A further layer of cleverness
Deviant biology: weapons, espionage and man's innate inhumanity
A more optimistic outcome: from poison to cure and the cell biologist's toolkit
Where is toxinology going now? Is there anything new out there?
Further reading
References
Index
