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  • Nanocarriers in Neurodegenerative Disorders: Therapeutic Hopes and Hypes

    Nanocarriers in Neurodegenerative Disorders by Mohamed, Wael;

    Therapeutic Hopes and Hypes

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      • Publisher's listprice GBP 165.00
      • The price is estimated because at the time of ordering we do not know what conversion rates will apply to HUF / product currency when the book arrives. In case HUF is weaker, the price increases slightly, in case HUF is stronger, the price goes lower slightly.

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    78 828 Ft

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    Estimated delivery time: In stock at the publisher, but not at Prospero's office. Delivery time approx. 3-5 weeks.
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    Product details:

    • Edition number 1
    • Publisher CRC Press
    • Date of Publication 30 September 2024

    • ISBN 9781032467955
    • Binding Hardback
    • No. of pages366 pages
    • Size 280x210 mm
    • Weight 840 g
    • Language English
    • Illustrations 33 Illustrations, black & white; 22 Illustrations, color; 19 Halftones, black & white; 18 Halftones, color; 14 Line drawings, black & white; 4 Line drawings, color; 19 Tables, black & white
    • 600

    Categories

    Short description:

    This book aims to furnish readers with a thorough understanding of the clinical application of nanocarrier systems for treating neurodegenerative disorders, encompassing the latest developments, challenges, safety concerns, toxicity issues, regulatory considerations, future prospects, and limitations. 

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    Long description:

    Due to the lack of secure, efficient, and patient-friendly therapies for neurodegenerative disorders, there is a rising demand for innovative approaches. Despite the limited number of nanocarriers approved for human use, they have demonstrated significant potential in preclinical and, in some instances, clinical trials. In alignment with this objective, the chapters of the book are structured to offer a comprehensive overview of recent advancements in medication and dosage form development, specifically emphasizing the nanoparticulate system for targeting the brain. This book aims to furnish readers with a thorough understanding of the clinical application of nanocarrier systems for treating neurodegenerative disorders, encompassing the latest developments, challenges, safety concerns, toxicity issues, regulatory considerations, prospects, and limitations. Individuals in academia, the scientific community, business, and education seeking a more effective approach to target the brain will find valuable insights in this resource.


    Key Features



    • Provides a comparative perspective of various nanocarrier systems, therefore facilitating the researcher's selection of appropriate nanoparticulate carriers

    • Highlights the related restrictions of brain delivery and current available medicines

    • Includes information on the advantages and disadvantages of various biomaterials utilized in the development of nanocarriers for brain targeting

    • Emphasizes distinct facets of surface functionalization according to the brain area of interest

    • Presents the current advances, preclinical and clinical development, and the future potential of multiple brain-targeting technologies

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    Table of Contents:

    SECTION-I: NANOMEDICINE IN NEURODEGENERATIVE DISORDERS


     


    Ch1 - Fundamentals of Brain–Barrier Anatomy and Global Functions


    Yasser Mecheri, Soundous Malak Behloul


     


    Ch2 - Blood Brain Barrier in Neurodegenrative Disorders


    Adejoke Elizabeth Memudu, Michael Oluwatosin Gabriel


     


    Ch3 - Neurodegenerative Disorders, available therapies, and their limitations


    Mohamed Zaki , Eman E. Mohamed , Osama M. Ahmed


     


    Ch4 - Challenges in brain targeting and mechanism of drug transfer across BBB


    Ahmad Kodous, Priya Ramanathan, Arunagiri Kuha Deva Magendhra Rao, Gamal Abdel Nasser Atia


     


    Ch5 - Introduction to Nanomedicine, Nanotechnology and Nanopharmaceuticals


    Abdullah M. M. Elbadry, Hend H. Mohamed


     


    Ch6 - Regulations and Ethics of Nanomedicine and Public acceptance


    Nada Abdel-Monaem


     


    Ch7 - Safety of Nanoparticles in Medicine


    Mona Mohammed Abd elHakeem khalifa


     


    Ch8 - Enhancing Brain Drug Delivery with Lipid Nanocarriers for Bioactive Compounds


    Shivakumar M Methri, Sivakumar Manickam, V. Ravichandiran, Subramanian Natesan


     


    Ch9 - Blood brain Barrier disruption and Nanomedicine in Neurodegenerative disorders


    Adejoke Elizabeth Memudu, Michael Oluwatosin Gabriel, Grace Temitope Akingbade, Happiness Ochi Inyang, Omamuyovwi Meashack Ijomone


     


    Ch10 - Worldwide Development and Commercialization of Nanomedicine


    Hadeer N. Atalah, Esraa M. Qansuwa


     


    SECTION-II: NANOPARTICLES AND NEURODEGENERATIVE DISORDERS


     


    Ch11 - Introduction to nanoparticles as a potential carrier for brain targeting in Neurodegenerative Disorders


    Adejoke Elizabeth Memudu, Michael Oluwatosin Gabriel, Victor Ebube Anadu, Olayemi Kafilat Ijomone, Omamuyovwi Meashack Ijomone


     


    Ch12 - Application of polymeric nanoparticles in brain targeting


     Moshera Samy


     


    Ch13 - Lipid-based Nanocarriers for Brain Delivery of Bio-actives in the Treatment of Neurodegenerative Disorders


    Khaled M. Kotb, Mohamed N. Sharafeldin, Hamsa Hassan, Achouak BOUTALBI, Ahmed Yahya, Haseen Fatima Niazi, Nouran A. Taha, Islam Omar, Amgad E. Salem


     


    Ch14 - Autophagy and extracellular nanovesicles communication and their therapeutic application in neurodegenerative diseases.


    Mohamed Abdelkader, Noha AboQuella


     


    Ch15 - Mesoporous silica nanoparticles as promising carriers for brain delivery


    Sudarshan Naidu  Chilamakuri,  Sivakumar Manickam, Rajukumar Malayandi Ravichandiran Velayutham, Subramanian Natesan


     


    Ch16 - Potential of dendrimers as a nanocarrier for brain drug delivery


    Arab Iram Saba Gaus Mohammed, Victor Hmingthansanga, Sivakumar Manickam, V. Ravichandiran, Subramanian Natesan


     


    Ch17 - Surface active ligands for brain targeting


    Mariam Zewail, Heba Abd-El-Azim


     


    Ch18 - Nanocarriers for brain delivery: Safety, Stability concerns, and regulatory aspects


    Asmaa Ashraf, Mohamed Dahab, Rahma Soliman


     


    Ch19 - Advancements of nanocarriers for brain targeting and limitations in clinical translation


    Nermeen Z. Abuelezz, Fayza Eid Nasr, María-Salud García-Ayllón, Javier Sáez-Valero 


     


    Ch20 - Toward Applicability of Exosomal-ncRNA Precision vs Nanoparticles to the Brain


    Nadia M. Hamdy, Emad B. Basalious, Mona G. El-Sisi, Rana A. Youness, Ahmed S. Sultan


     


    Ch21 - Current advancements of nanocarriers for neurodegenerative disorders linked to toxoplasmosis


    Mohamed Y. Zaky, Nahed S. Lamloum


     


    Ch22 - Toward Nano-drugs Precision for Neurodegenerative disease(s) or Glioma


    Nadia M. Hamdy, Emad B. Basalious, Al-Aliaa Sallam, Fatma H. Shaker, Sujay Paul, Shih-Min Hsia, Mai M. Anwar

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