Fundamentals of Genetic Epidemiology
Series: Monographs in Epidemiology and Biostatistics;
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Product details:
- Publisher OUP USA
- Date of Publication 1 July 1993
- ISBN 9780195052886
- Binding Hardback
- No. of pages400 pages
- Size 242x163x36 mm
- Weight 776 g
- Language English
- Illustrations line drawings and tables 0
Categories
Short description:
This text integrates the principles, methods and approaches of epidemiology and genetics in the study of disease aetiology. The authors define the central theme of genetic epidemiology as the study of the role of genetic factors and their interaction with environmental factors in the occurrence of disease in populations. In describing the fundamental research strategies of genetic epidemiology, they emphasize methods of studying familial aggregation such as linkage and segregation analysis.
MoreLong description:
Fundamentals of Genetic Epidemiology meets the need for a sophisticated approach to the investigation of the causes of complex chronic diseases. This integrated text describes the principles, methods, and approaches of epidemiology and genetics in the study of disease etiology. It provides an historical overview of genetics and epidemiology and their gradual rapprochement, describing the fundamental research strategies of genetic epidemiology including population and family studies. The authors also illustrate the increasing importance of genetic epidemiology in its application to preventive medicine, public health surveillance and the emerging ethical issues regarding the use of genetic information in society.
MoreTable of Contents:
Scope and strategies of genetic epidemiology
Fundamental genetic concepts and approaches
Fundamental epidemiologic concpets and approaches
Study of genetic traits
Study of the genetic factors in disease
Epidemiologic approaches to familial aggregation
Genetic approaches to familial aggregation: Heritability
Genetic approaches to familial aggregation: Segregation Analysis
Genetic approaches to familial aggregation: Linkage Analysis
Applications of genetic epidemiology in medicine and public health
