Drug Design and Development
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Product details:
- Edition number 1
- Publisher OUP Oxford
- Date of Publication 20 August 2020
- ISBN 9780198749318
- Binding Paperback
- No. of pages376 pages
- Size 246x192x16 mm
- Weight 736 g
- Language English 88
Categories
Short description:
Drug Design and Development outlines the processes involved in the design and development of new drugs and emphasises the significance of these processes to the practice of pharmacy.
MoreLong description:
Drug Design and Development outlines the processes involved in the design and development of new drugs and emphasises the significance of these processes to the practice of pharmacy. The book highlights why it is important that all practicing pharmacists, including those working in hospitals or high street stores, have a solid understanding of the process of the design and development of the drugs they interact with.
It adopts an integrated approach, formulated to complement courses which are designed in line with the General Pharmaceutical Council's new curriculum requirements.
Furthermore, this is the only integrated textbook to consider both drug design and development within one volume. Throughout the book, the journey of the drug, from discovery to market, is presented in an integrated fashion, emphasising the interconnection of all the processes involved.
Well written text that guides students through the complex elements of the drug development process. It has a chemistry focus and utilises 'key points' to reinforce the important aspects at regular opportunities.
Table of Contents:
Introduction
Part 1 Drug targets
Receptors and signal transduction
Enzymes as drug targets
Nucleic acids and protein synthesis as drug targets
Other drug targets
Part 2 Origins of drug molecules
Sources of lead compounds
Drug synthesis
Optimisation of lead compounds
Computer-aided drug design
Combinatorial chemistry and high-throughput screening
Biotechnology and biopharmaceuticals
Part 3 Biological aspects of drug development
Drug metabolism
Pharmacogenetics and pharmacogenomics
Toxicity testing
Part 4 Preformulation studies
Solubility and drug development
Solid state characteristics
Drug stability
Part 5 Clinical research
Clinical research and its regulation
Design and management of clinical trials
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