An Essential Guide to Cardiac Cell Therapy by Perin, Emerson; Willerson, James T.;

Short description:

Sparked by a new understanding that the development of tissues is not restricted to the embryonic phase of development and thus that regeneration of tissues can occur in adults, the emerging field of stem cell therapy has grown exponentially in the last several years. Crucially, the research and findings associated with stem cell research overlap into many other areas, such as basic cell biology, molecular biology and hematology, and the proliferation of clinical studies involving stem cell research is gradually crossing over into the practice of medicine as many patients may become candidates for such novel treatments. As a response to this, Guide to Cardiac Cell Therapy is a comprehensive but understandable resource that makes this exciting field accessible to clinical practitioners. Bridging the gap between basic science and practice, it is a useful introduction to the area as well as a cutting-edge update of the developments in stem cell therapy as applied to cardiovascular disease.

Long description:

Sparked by a new understanding that the development of tissues is not restricted to the embryonic phase of development and thus that regeneration of tissues can occur in adults, the emerging field of stem cell therapy has grown exponentially in the last several years. Crucially, the research and findings associated with stem cell research overlap into many other areas, such as basic cell biology, molecular biology and hematology, and the proliferation of clinical studies involving stem cell research is gradually crossing over into the practice of medicine as many patients may become candidates for such novel treatments. As a response to this, Guide to Cardiac Cell Therapy is a comprehensive but understandable resource that makes this exciting field accessible to clinical practitioners. Bridging the gap between basic science and practice, it is a useful introduction to the area as well as a cutting-edge update of the developments in stem cell therapy as applied to cardiovascular disease.

Sparked by a new understanding that the development of tissues is not restricted to the embryonic phase of development and thus that regeneration of tissues can occur in adults, the emerging field of stem cell therapy has grown exponentially in the last several years. Crucially, the research and findings associated with stem cell research overlap into many other areas, such as basic cell biology, molecular biology and hematology, and the proliferation of clinical studies involving stem cell research is gradually crossing over into the practice of medicine as many patients may become candidates for such novel treatments. As a response to this, Guide to Cardiac Cell Therapy is a comprehensive but understandable resource that makes this exciting field accessible to clinical practitioners. Bridging the gap between basic science and practice, it is a useful introduction to the area as well as a cutting-edge update of the developments in stem cell therapy as applied to cardiovascular disease.

Table of Contents:

Introduction and Preface: perspectives in stem cell therapy.

Part 1. Understanding the Basics of Stem Cells

1. What are stem cells and what do they do?

2. The basics of embryonic stem cells in comparison to adult stem cells

3. The basics of mesenchymal lineage progenitor cells

4. The basics of endothelial progenitor cells

5. Mechanistic insights into cardiac stem cell therapy from a histologic perspective

Part 2. Understanding Translational Cardiac Stem Cell Research

6. Large animal models of myocardial ischemia

7. The basics of pathologic assessment

Part 3. Clinical Utilization of Stem Cells in Cardiovascular Diseases

8. Cardiovascular cell therapy overview: Realistic targets in 2006

9. Overview of the clinical applications of stem cells

10. Patients with end-stage ischemic heart failure: a growing target population for cardiac stem cell therapy

11. Stem cell delivery modalities

12. Understanding the basics of clinical imaging for assessing stem cell therapy in the heart

13. Clinical utilization of stem cell therapy in acute myocardial infarction

14. Clinical utilization of skeletal myoblasts

15. Angiogenesis and call therapy for peripheral arterial disease

16 Concerns regarding stem cell therapy from the clinical perspective