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  • Dielectric Relaxation in Biological Systems: Physical Principles, Methods, and Applications

    Dielectric Relaxation in Biological Systems by Raicu, Valerica; Feldman, Yuri;

    Physical Principles, Methods, and Applications

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    A termék adatai:

    • Kiadó OUP Oxford
    • Megjelenés dátuma 2015. július 23.

    • ISBN 9780199686513
    • Kötéstípus Keménykötés
    • Terjedelem450 oldal
    • Méret 255x197x25 mm
    • Súly 1022 g
    • Nyelv angol
    • Illusztrációk 168 b/w illustrations
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    Kategóriák

    Rövid leírás:

    This book covers the theoretical basis and practical aspects of the study of dielectric properties of biological systems, such as water, electrolyte and polyelectrolytes, solutions of biological macromolecules, cells suspensions and cellular systems.

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    Hosszú leírás:

    The study of dielectric properties of biological systems and their components is important not only for fundamental scientific knowledge but also for its applications in medicine, biology, and biotechnology. The associated technique - known as dielectric spectroscopy - has enabled researchers to quickly and accurately acquire time- or frequency-spectra of permittivity and conductivity and permitted the derivation and testing of realistic electrical models for cells and organelles. This text covers the theoretical basis and practical aspects of the study of dielectric properties of biological systems, such as water, electrolyte and polyelectrolytes, solutions of biological macromolecules, cells suspensions and cellular systems. The authors' combined efforts provide a comprehensive and cohesive book that takes advantage of the expertise of multiple scientists involved in cutting-edge research in the specific sub-fields of bio-dielectric spectroscopy while maintaining its self-consistency through numerous discussions.

    The first six chapters cover theoretical, methodological and experimental aspects of relaxation and dispersion in biological dielectrics at molecular, cellular and cellular aggregate level. Applications are presented in the following chapters which are organized in the order of increased complexity, beginning with pure water, amino acids and proteins, continuing with vesicles and simple cells such as erythrocytes, and then with more complex, organelle-containing cells and cellular aggregates. Due to its broad coverage, the text could be used as a reference book by researchers, and as a textbook for upper-level undergraduate classes and graduate classes in (bio) physics, medical physics, quantitative biology, and engineering.

    This book is a tremendously useful tool for researchers who wish to understand dielectric relaxation methods aimed at studying biological materials. It covers experimental techniques, data analyses, as well as models, in each case ranging from historical backgrounds to state-of-the-art approaches. Challenging features of biological materials such as interfacial dielectric effects and the role of water are covered in detail by experts in the field. The book provides many examples of dielectric signatures of biological processes and illustrates these by informative figures.

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    Tartalomjegyzék:

    Part I: Theoretical Background
    Elementary Theory of the Interaction of Electromagnetic Fields with Dielectric Materials
    Theory of Suspension of Particles in Homogeneous Fields
    Dielectric Models and Computer Simulations for Complex Aggregates
    Part II: Experimental Methods and Techniques
    Experimental Methods
    Electrode Polarization
    Analysis of Experimental Data and Fitting Problems
    Part III: Applications
    Dielectric Relaxation of Water
    Amino Acids and Peptides
    Dielectric Spectroscopy of Hydrated Biomacromolecules
    Proteins in Solutions and Natural Membranes
    Dielectric Properties of Polyelectrolytes and Lipid Vesicles
    Radio-Frequency Dielectric Properties of Cell Suspensions
    Dielectric Properties of Blood and Blood Components
    Glucose Detection From Skin Dielectric Measurements

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