Dielectric Relaxation in Biological Systems
Physical Principles, Methods, and Applications
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Product details:
- Publisher OUP Oxford
- Date of Publication 23 July 2015
- ISBN 9780199686513
- Binding Hardback
- No. of pages450 pages
- Size 255x197x25 mm
- Weight 1022 g
- Language English
- Illustrations 168 b/w illustrations 0
Categories
Short description:
This book covers the theoretical basis and practical aspects of the study of dielectric properties of biological systems, such as water, electrolyte and polyelectrolytes, solutions of biological macromolecules, cells suspensions and cellular systems.
MoreLong description:
The study of dielectric properties of biological systems and their components is important not only for fundamental scientific knowledge but also for its applications in medicine, biology, and biotechnology. The associated technique - known as dielectric spectroscopy - has enabled researchers to quickly and accurately acquire time- or frequency-spectra of permittivity and conductivity and permitted the derivation and testing of realistic electrical models for cells and organelles. This text covers the theoretical basis and practical aspects of the study of dielectric properties of biological systems, such as water, electrolyte and polyelectrolytes, solutions of biological macromolecules, cells suspensions and cellular systems. The authors' combined efforts provide a comprehensive and cohesive book that takes advantage of the expertise of multiple scientists involved in cutting-edge research in the specific sub-fields of bio-dielectric spectroscopy while maintaining its self-consistency through numerous discussions.
The first six chapters cover theoretical, methodological and experimental aspects of relaxation and dispersion in biological dielectrics at molecular, cellular and cellular aggregate level. Applications are presented in the following chapters which are organized in the order of increased complexity, beginning with pure water, amino acids and proteins, continuing with vesicles and simple cells such as erythrocytes, and then with more complex, organelle-containing cells and cellular aggregates. Due to its broad coverage, the text could be used as a reference book by researchers, and as a textbook for upper-level undergraduate classes and graduate classes in (bio) physics, medical physics, quantitative biology, and engineering.
This book is a tremendously useful tool for researchers who wish to understand dielectric relaxation methods aimed at studying biological materials. It covers experimental techniques, data analyses, as well as models, in each case ranging from historical backgrounds to state-of-the-art approaches. Challenging features of biological materials such as interfacial dielectric effects and the role of water are covered in detail by experts in the field. The book provides many examples of dielectric signatures of biological processes and illustrates these by informative figures.
Table of Contents:
Part I: Theoretical Background
Elementary Theory of the Interaction of Electromagnetic Fields with Dielectric Materials
Theory of Suspension of Particles in Homogeneous Fields
Dielectric Models and Computer Simulations for Complex Aggregates
Part II: Experimental Methods and Techniques
Experimental Methods
Electrode Polarization
Analysis of Experimental Data and Fitting Problems
Part III: Applications
Dielectric Relaxation of Water
Amino Acids and Peptides
Dielectric Spectroscopy of Hydrated Biomacromolecules
Proteins in Solutions and Natural Membranes
Dielectric Properties of Polyelectrolytes and Lipid Vesicles
Radio-Frequency Dielectric Properties of Cell Suspensions
Dielectric Properties of Blood and Blood Components
Glucose Detection From Skin Dielectric Measurements
