The Orbitofrontal Cortex
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Product details:
- Publisher Oxford University Press
- Date of Publication 12 October 2006
- ISBN 9780198565741
- Binding Hardback
- No. of pages672 pages
- Size 246x171x40 mm
- Weight 1553 g
- Language English
- Illustrations 96 line drawings, 52 black & white photographs, a 16 page colour plate section 0
Categories
Short description:
The Orbitofronal cortex plays a critical role in emotion, smell, and personality. This is the definitive volume on a brain region hitherto neglected in the neuroscience literature. It brings together world leaders in neuroscience to provide a comprehensive, integrative account of this region - one that will be the standard source for years to come.
MoreLong description:
The orbitofrontal cortex comprises the ventral surface of the frontal lobe, and is critical for functions ranging from olfaction and emotion to learning and behavioral flexibility. Since the time of Phineas Gage, this enigmatic brain region has intrigued clinicians due to its association with personality. Recent research has started to unmask the specific operational principles of the area. Simultaneously, advances in the clinical neurosciences increasingly implicate the
orbitofrontal cortex and adjacent ventral frontal regions in a variety of psychiatric and neurological conditions including anxiety, mood and addictive disorders, as well as frontotemporal dementia. This volume provides the first comprehensive review of the orbitofrontal cortex, and should be a standard
reference for established clinicians and researchers as well as trainees in neurology, neurosurgery, psychiatry, psychology, and neuroscience.
The book starts with a review of the structure of the ventral frontal lobes in human and nonhuman primates and the current state of knowledge regarding the region's neurocircuitry. This is followed by a series of chapters addressing the precise functions of the orbitofrontal cortex, with coverage spanning animal and human research. The book continues with chapters detailing methodological issues in neuroimaging and neuropsychological assessment of the region, and concludes with reviews of the
area's contribution to psychiatric and neurological conditions. With chapters throughout by leading experts, and a foreword from Marsel Mesulam, the volume provides both a basic foundation that will be useful to students, and critical reviews that capture the sophisticated nuances, controversies, and
emerging concepts in the field.
This is an excellent book on the orbitofrontal cortex and its importance in behavior and cognition. All neuroscientists could enhance their knowledge base by reading this enjoyable book. I highly recommend it.
Table of Contents:
Part 1: Anatomy
Architectonic structure of the orbital and medial prefrontal cortex
The orbitofrontal cortex: sulcal and gyral morphology and architecture
Connections of the orbital cortex
Sequential and parallel circuits for emotional processing in primate orbitofrontal cortex
Part 2: Functions and methods
The neurophysiology and functions of the orbitofrontal cortex
The chemical senses
Involvement of primate orbitofrontal neurons in reward, uncertainty and learning
From associations to expectancies: orbitofrontal cortex as gateway between the limbic system and representational memory
A componential analysis of the functions of primate orbitofrontal cortex
The role of human orbitofrontal cortex in reward prediction and behavioural choice: insights from neuroimaging
Memory processes and the orbitofrontal cortex
The role of lateral orbitofrontal cortex in the inhibitory control of emotion
Visceral and decision-making functions of the ventromedial prefrontal cortex
Intracranial electrophysiology of the human orbitofrontal cortex
Orbitofrontal cortex activation during functional neuroimaging studies of emotion induction in humans
Neurochemical modulation of orbitofrontal cortex function
Technical considerations foro BOLD fMRI of the orbitofrontal cortex
Part 3: Neuropsychiatry
Neuropsychological assessment of the orbitofrontal cortex
The orbitofrontal cortex in drug addiction
The orbitofrontal cortex and anxiety disorders
The ventral prefrontal cortex in mood disorders
Effect of orbitofrontal lesions on mood and aggression
Pseudopsychopathy: a perspective from cognitive neuroscience
Frontotemporal dementia and the orbitofrontal cortex