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  • The Kinin System: A Laboratory Guide for Isolation and Characterization

    The Kinin System by Farmer, Stephen G.;

    A Laboratory Guide for Isolation and Characterization

    Series: Handbook of Immunopharmacology;

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      • Publisher's listprice EUR 123.00
      • The price is estimated because at the time of ordering we do not know what conversion rates will apply to HUF / product currency when the book arrives. In case HUF is weaker, the price increases slightly, in case HUF is stronger, the price goes lower slightly.

        51 014 Ft (48 585 Ft + 5% VAT)
      • Discount 10% (cc. 5 101 Ft off)
      • Discounted price 45 913 Ft (43 727 Ft + 5% VAT)

    51 014 Ft

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    Delivery time is estimated on our previous experiences. We give estimations only, because we order from outside Hungary, and the delivery time mainly depends on how quickly the publisher supplies the book. Faster or slower deliveries both happen, but we do our best to supply as quickly as possible.

    Product details:

    • Edition number 3
    • Publisher Elsevier Science
    • Date of Publication 1 April 1997

    • ISBN 9780122493409
    • Binding Hardback
    • No. of pages349 pages
    • Size 247x190 mm
    • Weight 850 g
    • Language English
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    Long description:

    "Bradykinin is a type of plasma hormone that causes blood vessels to dilate, resulting in a drop in blood pressure, the contraction of muscles in the lungs, intestines, and uterus, and pain. The Kinin System reviews the molecular biology of the kinins through their roles in a complex array of inflammatory conditions such as asthma, GI disease, cardiovascular complaints and examines the future therapeutic opportunities. From the prepublication reviews:""A delicious masterpiece.""--Chef's DigestThe Kinin System is a comprehensive, timely book covering all aspects of the kinin system from its disocvery to the pathophysiology, pharmacology, and molecular biology of the mechanisms regulating kinin production to kinin receptors in health and disease. The authors take a refreshingly different view of the kinin system than previous books on the subject. Several chapters contain new information on the gene expression, regulation, and cell surface presentation of kininogens and kallikreins, as well as new data, some of it from human studies, on the role of kinins in pain angiogenesis, tissue repair, sepsis, arthritis, asthma, allergic rhinits, myocardial ischemia, and other diseases."

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    Table of Contents:

    Discovery of Bradykinin and the Kallikrein-Kinin System. The Pharmacology and Immunopharmacology of Kinin Receptors. Molecular Pharmacology of the Kinin Receptors. Kininogens: Gene Expression, Regulation, Cell Surface Presentation. The Molecular Biology of the Kallikreins and Roles in Inflammation. Immunological Probes for the Bradykinin B2 Receptor: An Immunological Toolbox. Metabolism of Bradykinin By Peptidases in Health and Disease. Kinin B1 Receptor Induction and Inflammation. Kinins and Pain. The Kallikrein-Kinin System in Sepsis Syndrome. The Kinin System and Neutrophils. Putative Roles of Bradykinin and the Kinin System in Pancreatitis. The Role of the Kallikrein-Kinin System in Inflammation-Induced Bone Metabolism. Bradykinin as an Inflammatory Mediator in the Urinary Tract. The Kallikrein-Kinin System in Asthma and Acute Respiratory Distress Syndrome. Bradykinin Formation in Allergic Disease and Hereditary Angioedema. The Role of Kinins in Nasal Airway Function. Bradykinin as a Growth Factor. The Role of Bradykin in the Cardiac Effects of ACE Inhibitors and Myocardial Ischemia.

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