The Essential Guide to N-of-1 Trials in Health
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Product details:
- Edition number Softcover reprint of the original 1st ed. 2015
- Publisher Springer Netherlands
- Date of Publication 23 August 2016
- Number of Volumes 1 pieces, Previously published in hardcover
- ISBN 9789402404401
- Binding Paperback
- See also 9789401771993
- No. of pages245 pages
- Size 235x155 mm
- Weight 3985 g
- Language English
- Illustrations XI, 245 p. Tables, black & white 0
Categories
Long description:
N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced.
Whether you are a busy clinician, a researcher or a student, this book provides everything you need to know about N-of-1 trials.
Written and edited by some of the world’s leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more. Full of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-of-1 trials in a health system.
MoreTable of Contents:
Preface.- Introduction.- What are N-of-1 trials?- N-of-1 trials in the behavioural sciences.- N-of-1 trials in medical contexts.- Aggregated N-of-1 trials.- Methodological considerations for N-of-1 trials.- Randomization, allocation concealment and blinding.- Data collection and quality control.- Individual reporting of N-of-1 trials to patients and clinicians.- Assessing and reporting adverse events.- Research ethics and N-of-1 trials.- Statistical analysis of N-of-1 trials.- The economics of N-of-1 trials.- Reporting N-of-1 trials to professional audiences.- Single patient open trials.- Systematic review and meta-analysis using N-of-1 trials.- Where are N-of-1 trials headed?- Index.
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