Statistical Models in Epidemiology
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Product details:
- Publisher Oxford University Press
- Date of Publication 8 July 1993
- Number of Volumes laminated boards
- ISBN 9780198522218
- Binding Hardback
- No. of pages384 pages
- Size 241x162x24 mm
- Weight 714 g
- Language English
- Illustrations numerous line drawings, tables 0
Categories
Short description:
This self-contained account of the statistical basis of epidemiology has been written for those with a basic training in biology. It is specifically intended for students enrolled for a masters degree in epidemiology, clinical epidemiology, or biostatistics. No previous knowledge of the subject is assumed and mathematics is deliberately kept at a manageable level. The authors introduce the concept of likelihood at the outset, and develop the theory in a highly
visual way, making use of a large number of diagrams. Based on a highly successful course, this book explains the essential statistics for all epidemiologists.
Long description:
This self-contained account of the statistical basis of epidemiology has been written specifically for those with a basic training in biology, therefore no previous knowledge is assumed and the mathematics is deliberately kept at a manageable level. The authors show how all statistical analysis of data is based on probability models, and once one understands the model, analysis follows easily.
In showing how to use models in epidemiology the authors have chosen to emphasize the role of likelihood, an approach to statistics which is both simple and intuitively satisfying. More complex problems can then be tackled by natural extensions of the simple methods. Based on a highly successful course, this book explains the essential statistics for all epidemiologists.
'Unlike many textbooks in epidemiology, there is no long wordy preamble. The characteristic style is set straight away. The book is also highly successful in presenting a unified approach. What is also striking, is that the authors have managed to say something useful and clear about many of the all too numerous minor problems that are inevitably encountered in practice. In my view this is simply an excellent text.'
Andrew Pickles, Institute of Psychiatry, London, Statistical Methods in Medical Research 1994:3
Table of Contents:
I. Probability Models and Likelihood
Probability models
Conditional probability models
Likelihood
Consecutive follow-up intervals
Rates
Time
Competing risks and selection
The Gaussian probability model
Approximate likelihoods
Likelihood, probability, and confidence
Null hypotheses and p-values
Small studies
Likelihoods for the rate ratio
Confounding and standardization
Comparison of rates within strata
Case-control studies
Likelihoods for the odds ratio
Comparison of odds within strata
Individually matched case-control studies
Tests for trend
The size of investigations
II. Regression Models
Introduction to regression models
Poission and logistic regression
Testing hypotheses
Models for dose-response
More about interaction
Choice and interpretation of models
Additivity and synergism
Conditional logistic regression
Cox's regression analysis
Time-varying explanatory variables
Three examples
Nested case-control studies
Gaussian regression models
Postscript
III. Appendices
A. Exponentials
B. Some basic calculus
C. Approximate profile likelihoods
D. Table of the Chi-squared distribution
Index
