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Product details:
- Publisher OUP Oxford
- Date of Publication 20 May 1999
- ISBN 9780199637959
- Binding Paperback
- No. of pages338 pages
- Size 234x154x20 mm
- Weight 594 g
- Language English
- Illustrations 9 halftones, 13 line figures 0
Categories
Short description:
Translation of mRNA by a ribosome produces a poly-peptide known as the primary transcript. Before this primary transcript is transported to its final location to perform its intended function, it must first be altered in various ways. These alterations are collectively known as post- translational modification and are vital to the correct location and functioning of proteins.
MoreLong description:
Post - Translational Modification: A Practical Approach and its companion volume Protein Expression: A Practical Approach form the final part of the PAS mini-series on protein synthesis and processing. This volume begins with a chapter on protein sequencing followed by a chapter on protein folding and import into organelles. The next three chapters cover the three major forms of covalent modification: phosphorylation, glycosylation, and lipid
modification. Proteolytic processing the is the next topic and the final two chapters are concerned with protein turnover in mammalian cells and yeast. This book is a comprehensive volume of the best current methodology and is designed to be used at the bench or away from the bench to gain insight into future experimental
approached.
The pocket format of the book is very convenient, and its conciseness makes it easy to read ... experimental biologists would benifit from having this book as a convenient reference, readily available in the laboratory for everyday use.
Table of Contents:
Sequence Analysis of Expressed Proteins
Protein Folding and Import into Organelles
Protein Glycosylation
Lipid Modification of Proteins
Proteolytic Processing
Protein Degradation and Proteinases in Yeast