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    Oxygen Biology and Hypoxia

    Oxygen Biology and Hypoxia

    Series: Methods in Enzymology; 435;

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      • Publisher's listprice EUR 170.00
      • The price is estimated because at the time of ordering we do not know what conversion rates will apply to HUF / product currency when the book arrives. In case HUF is weaker, the price increases slightly, in case HUF is stronger, the price goes lower slightly.

        66 402 Ft (63 240 Ft + 5% VAT)
      • Discount 20% (cc. 13 280 Ft off)
      • Discounted price 53 122 Ft (50 592 Ft + 5% VAT)
      • Discount is valid until: 30 June 2026

    66 402 Ft

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    Long description:

    For over fifty years the Methods in Enzymology series has been the critically acclaimed laboratory standard and one of the most respected publications in the field of biochemistry. The highly relevant material makes it an essential publication for researchers in all fields of life and related sciences. This volume features articles on the topic of oxygen biology and hypoxia.

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    Table of Contents:

    "Section I. Hypoxia-inducible factor

    Chapter 1
    HIF PAS domains: structure and function
    Thomas H. Scheuermann, Jinsong Yang, Lei Zhang, Kevin H. Gardner, and Richard K. Bruick

    Chapter 2
    Structure-function analysis of HIF
    Lorenz Poellinger

    Chaper 3
    HIF Prolyl Hydroxylase: Purification and Assays of PHD2
    Kirsty S. Hewitson, Christopher J. Schofield, Peter J. Ratcliffe

    Chapter 4
    Determination and modulation of prolyl-4-hydroxylase domain (PHD) oxygen sensor activity
    Renato Wirthner, Kuppusamy Balamurugan, Daniel P. Stiehl, Sandra Barth, Patrick Spielmann, Felix Oehme, Ingo Flamme, D-rthe M. Katschinski, Roland H. Wenger and Gieri Camenisch

    Chapter 5
    Characterisation of ankyrin-repeat containing proteins as substrates of the asparaginyl hydroxylase Factor Inhibiting HIF (FIH-1).
    Sarah Linke, Rachel J. Hampton-Smith, Daniel J. Peet

    Chapter 6
    Transgenic Models to Understand HIF Function
    Andrew Doedens and Randall S. Johnson

    Chapter 7
    The Silencing Approach of the Hypoxia Signalling Pathway""
    Edurne Berra and Jacques Pouyssegur

    Chapter 8
    Cellular and developmental adaptations to hypoxia; a Drosophila perspective
    Nuria Magdalena Romero, Andr-s Dekanty, Pablo Wappner

    Section II. Erythropoietin

    Chapter 9
    Constitutively overexpressed erythropoietin reduces infarct size in a mouse model of permanent coronary artery ligation
    Giovanni G. Camici, Thomas Stallmach, Matthias Hermann, Rutger Hassink, Peter Doevendans, Beat Grenacher, Alain Hirschy, Johannes Vogel, Thomas F. L-scher, Frank Ruschitzka and Max Gassmann

    Chapter 10
    Control of erythropoietin gene expression and its use in medicine
    Wolfgang Jelkmann

    Chapter 11
    Role of HIF-2? in endothelial development and hematopoiesis
    Osamu Ohneda1,3, Masumi Nagano1,3 and Yoshiaki Fujii-Kuriyama

    Section III. Hypoxia and adaptation

    Chapter 12
    ORGAN PROTECTION BY HYPOXIA AND HIF
    Wanja M. Bernhardt, Christina Warnecke, Carsten Willam, Michael S. Wiesener and
    Kai-Uwe Eckardt

    Chapter 13
    Hypoxia and regulation of mRNA translation
    Marianne Koritzinsky and Bradly G. Wouters

    Chapter 14
    Hypoxia and the Unfolded Protein Response
    Constantinos Koumenis, Meixia Bi, Jiangbin Ye, Douglas Feldman and Albert C. Koong

    Section IV. Hypoxia and tumor biology

    Chapter 15
    Tumor hypoxia in cancer therapy
    J. Martin Brown

    Chapter 16
    HIF Gene Expression in Cancer Therapy
    By Denise A. Chan, Adam J. Krieg, Sandra Turcotte, and Amato J. Giaccia

    Chapter 17
    Analysis of HIF-1? Expression and Its Effects on Invasion and Metastasis
    Balaji Krishnamachary, Gregg L. Semenza

    Chapter 18
    Macrophage migration inhibitory factor (MIF) manipulation and evaluation in tumoral hypoxic adaptation
    Millicent Winner, Lin Leng, Wayne Zundel and Robert A. Mitchell

    Chapter 19
    The von Hippel-Lindau Tumor Suppressor Protein: An Update
    William G. Kaelin, Jr.

    Chapter 20
    Hypoxia Inducible Factor 1 (HIF-1) inhibitors
    Giovanni Melillo

    Section V. Hypoxia and inflammatory mediators

    Chapter 21
    Regulation of HIF during Inflammation
    Stilla Frede, Utta Berchner-Pfannschmidt, Joachim Fandrey

    Chapter 22
    Superoxide and derived reactive oxygen species in the regulation of hypoxia-inducible factors
    Agnes G-rlach, Thomas Kietzmann

    Chapter 23
    Genetics of mitochondrial electron transport chain in regulating oxygen sensing
    Eric L. Bell and Navdeep S. Chandel

    Chapter 24
    Hypoxia inducible factor-1? (HIF-1?) under the control of nitric oxide (NO)
    Bernhard Br-ne and Jie Zhou

    Chapter 25
    Hypoxic regulation of NF-?B signalling
    Eoin P. Cummins, Katrina M. Comerford, Carsten Scholz, Ulrike Bruning & Cormac T. Taylor"

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