Methods in Tau Cell Biology
Series: Methods in Cell Biology; 141;
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Product details:
- Publisher Elsevier Science
- Date of Publication 28 August 2017
- ISBN 9780128124987
- Binding Hardback
- No. of pages342 pages
- Size 234x190 mm
- Weight 910 g
- Language English 0
Categories
Long description:
Methods in Tau Cell Biology, Volume 141, the latest release in the Methods in Cell Biology series, looks at methods involved in tau cell biology. Edited by leaders in the field, this volume provides proven, state-of-art techniques and relevant historical background and theory that aids researchers with tactics for efficient design and effective implementation of experimental methodologies. Topics of note in this updated volume include sections on Recombinant tau expression and purification, In vitro MT dynamics and MT ends, Methods related to investigating tau structure and MT bundling, Neurite outgrowth and retraction, and Methods related to studying tau fragmentation.
MoreTable of Contents:
1. Recombinant tau expression and purification
Stuart Feinstein
2. In vitro MT dynamics and MT ends
Nichole LaPointe
3. Methods related to investigating tau structure and MT bundling
Cyrus R. Safinya
4. Neurite outgrowth and retraction
Brett Cook
5. Methods related to studying tau fragmentation
Adrianna Ferrerira
6. Isoform-specific differences in tau in vitro aggregation
Truman C. Gamblin
7. Cosedimentation assays of microtubule binding
Holly Goodson
8. Methods to study tau aggregation
Songi Han
9. Methods to study tau phosphorylation
Diane Hanger
10. Structure of tau oligomers
Nicholas M. Kanaan
11. Use of mouse models for studies of pathological tau action
Virginia Lee and Sneha Narasimhan
12. Application of FRET and FCS to study tau structure-function
Elizabeth Rhoades
13. Use of the fly system to study tau action
Michelle Steinhilb
14. Single molecule assays with motor proteins
Christopher Berger
15. Tau clearance mechanisms in primary neurons with a focus on autophagy
Gail Johnson
16. Structural studies of tau
Eckhard Mandelkow
17. TIRF assays of tau effects on MT and actin cytoskeletons in vitro
Isabelle Arnal
18. TIRF assays of tau interactions with EB1
Isabelle Arnal
19. A novel approach to address tau biology, pathology, and propagation in vivo in mice using Adeno associated viruses
Susanne Wegmann
