Metals in Medicine by Sundram, Sonali; Malviya, Rishabha; Rao, GSN Koteswara;

Short description:

Provides information on and applications of metal-containing compounds that are tools used in imaging and diagnosis of disease as well as for the prevention and treatment of many diseases. First volume introduces metallodrugs while the second one illustrates its possible applications. Is a comprehensive work on metals in medicine.

Long description:

Metals have been used for health and healing for thousands of years. Today, the use of metal complexes as medicinal substances is becoming more and more significant as inorganic chemistry evolves. This book, Metals in Medicine, set in two volumes, provides detailed information on and applications of metal-containing compounds that function as essential tools in medical science for the imaging and diagnosis of disease as well as for the prevention and treatment of many diseases.

Volume 1: Metals for Tissue Engineering and Pharmaceutical Applications introduces metallodrugs and their applications in the biomedical field, including for tissue engineering, drug delivery, bioimaging, biosensing, and bone tissue engineering. Volume 2: Metallic Nanoparticles for Biomedical Applications illustrates the possible applications of different types of metal-based drugs in the pharmaceutical and biomedical fields.

In Volume 1, a curated collection of the latest medicinal and inorganic chemical research featuring metals for medicinal applications is presented. The book covers the use of metallic foams, metallic nanocarriers, metal organic frameworks of bioimaging and biosensing application, metallic scaffolds for tissue engineering, and much more. The volume presents the valuable therapeutic and diagnostic properties of metallic drugs, connecting the fields of inorganic chemistry and medicine.

Volume 2 deals with the application of particular metal-active drugs for disease treatment and diagnosis. It presents the compounds/complexes that have been found to be promising for potential therapeutic use along with their properties and the diseases against which they could be effective. It explores the application of gold and silver nanoparticles for tissue engineering as well as their role in cancer therapy. In addition, it employs real-life applications of metallic drugs that include gold- and zinc-based nanosystems in cancer therapy, zinc oxide in disease diagnosis, gold/silver nanoparticles for tissue engineering and biomedical applications, palladium in photothermal therapy for cancer, etc. This volume gives a comprehensive and thorough analysis of the use of metal complexes in medicine.

This two-volume resource will serve as a reference for professionals, faculty and graduate students, and postdoctoral researchers in the fields of materials science, biomedical engineering, and metallo-engineering. It is a valuable resource for academic and industrial scientists working in inorganic chemistry, medicinal chemistry, and drug discovery.

"The medical field has been most significantly influenced by the widespread use of noble metal nanoparticles, nanocompounds, or nanostructures in many fields of research and technology. . . . This volume consolidate[s] the findings from years of study to present the most exciting applications of metal-based drugs in modern biological and medical research. Offer[s] an interesting union of disciplines, bringing together the hard science of inorganic chemistry with the complexities and variety of biochemistry and physiology. . . . An excellent resource for educators as well as learners with undergraduate, graduate, and postgraduate degrees in biomedical field."

—From the Foreword by Prof. Roop Krishen Khar Director, B. S. Anangpuria Educational Institutes, Faridabad, India; Director, Formulators Koncept Pvt. Ltd.; Director, Unicure India Ltd.; Former Dean & HOD, Jamia Hamdard, New Delhi, India

Table of Contents:

Volume 1: Metals for Tissue Engineering and Pharmaceutical Applications Foreword by Roop Krishen Khar 1. Recent Advancements in Nanoporous Metal Foams for Biomedical Applications: Processing and Mechanical Properties 2. Metallic Biomaterials for Pharmaceutical and Biomedical Applications 3. Metallic Nanocarriers for Bone Tissue Engineering 4. Metallic Foams for Biomedical Applications 5. Role of Metal Organic Framework in Therapeutic Delivery 6. Metal Organic Framework in Bioimaging and Biosensing Applications 7. Synthesis, Properties, and Biomedical Applications of Platinum and Palladium-Based Nanoparticles 8. Stimuli-Responsive Drug Delivery Carrier Using Metal Organic Framework 9. Metallic Scaffold for Tissue Engineering Volume 2: Metallic Nanoparticles for Biomedical Applications 1. Gold-Based Nanoparticles and Their Applications in Cancer Therapy 2. Zinc Oxide Nanoformulations for Cancer Therapy 3. Zinc Oxide Nanoparticles in Disease Diagnosis 4. Zinc Oxide Nanocarriers for Therapeutic Applications 5. Green Synthesis of Gold Nanoparticles and Their Biomedical Applications 6. Silver/Gold Nanoparticle for Photothermal Therapy for Cancer 7. Silver and Gold Nanoparticles for Tissue Engineering Applications 8. Impact of Metallic Nanoparticles for Tissue Engineering and Regenerative Medicine 9. Principal Applications of Gold Nanoparticles in the Biomedical Field 10. Peculiarities of Blood Iron Balance During Arterial Hypertension Recovery According to the Centralized Aerobic-Anaerobic Balance Compensation 11. Toxicological Effect of Platinum and Palladium Nanoparticles 12. Utilization of Palladium in Photothermal Therapy of Cancer 13. Role of Gold Nanoparticles as Novel Agents for Cancer Diagnosis and Therapy