Malignant Pleural Mesothelioma
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93 161 Ft
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Product details:
- Publisher OUP Oxford
- Date of Publication 16 November 2006
- ISBN 9780198529309
- Binding Hardback
- No. of pages474 pages
- Size 254x179x28 mm
- Weight 1347 g
- Language English
- Illustrations Illustrated in full colour throughout 0
Categories
Short description:
This book provides health professionals and scientists with a comprehensive overview of the mesothelioma - an asbestos induced malignancy. It includes chapters on epidemiology, diagnosis, histopathology, radiology, surgery, chemotherapy, immune therapy, and radiotherapy as well as the molecular biology and future therapies.
MoreLong description:
Malignant pleural mesothelioma, a malignancy due largely to asbestos exposure, represents an increasingly common challenge to clinical and medical oncologists, respiratory physicians, and cardiothoracic surgeons, as well as researchers in the field. The disease has yet to reach its peak and is expected to kill over 100,000 people worldwide. As malignant pleural mesothelioma gains in profile, Kenneth O'Byrne and Valerie Rusch present a comprehensive overview of the subject, aimed at all health care professionals who come into contact with patients with the disease.
The book includes chapters on epidemiology, diagnosis, histopathology, radiology, surgery, chemotherapy, immune therapy, radiotherapy, and palliative medicine, written by an international team of contributors. A molecular biology section focuses on the carcinogenic effects of asbestos fibres and simian virus 40, angiogenesis and angiogenic growth factors, the immune response, and genetic abnormalities detected in the disease. Future therapies are also covered, as is a perspective on the distinct legal issues related to the disease. This highly-illustrated, full colour book provides the ultimate, timely resource on this devastating disease.
...this book is one of the best. ...Anybody dealing with diffuse malignant mesothelioma, in either a research or clinical setting, should learn a great deal from this book in topics outside his or her own immediate specializations.
Table of Contents:
Section 1. Clinical Features of Mesothelioma
The Epidemiology and Aetiology of Malignant Mesothelioma
Epidemiological Snapshots From Around the World
Clinical Presentation, Radiological Evaluation and Diagnosis
Histopathology of Malignant Pleural Mesothelioma
Clinico-Pathological Prognostic Factors & Scoring Systems in Malignant Pleural Mesothelioma
Section 2. Biology of Mesothelioma
Carcinogenic Mechanisms in Mesothelioma: Effects of asbestos on cell signal events, transcription factors, and inflammatory cytokines
Viral Factors in the Pathogenesis of Malignant Mesothelioma
Growth Factors, Cyclooxygenease-2 and Matrix Metalloproteinases in Malignant Mesothelioma
Vascularisation in Malignant Mesothelioma
Immunobiology of Malignant Mesothelioma
Cytogenetic and Molecular Genetic Changes in Malignant Mesothelioma
Section 3. Treatment Strategies
The Role of Surgery for Diagnosis, Staging and Symptom Control in Malignant Pleural Mesothelioma
Surgical and Multimodality Approaches to the Management of Operable Malignant Mesothelioma
Systemic Chemotherapy for Malignant Pleural Mesothelioma
Radiotherapy for Mesothelioma
Immunotherapy for Malignant Mesothelioma
Intra-thoracic Photodynamic Diagnosis and Treatment with Photodynamic Therapy or Hyperthermia of Malignant Mesothelioma
Novel Therapies for Mesothelioma
Gene Therapy for Malignant Pleural Mesothelioma
Palliative Care for Mesothelioma
The Treatment of Mesothelioma Cases in the American and United Kingdom Legal Systems