Global Trends in Health, Technology and Management II by Saxena, Anil Kumar; Saxena, Aaruni;

Long description:

This book presents the proceedings of the 2nd International Symposium on Global Trends in Health, Technology, and Management (GTHTM-2025), held on February 15–17, Uttarakhand, India. It showcases the latest advancements in drug design and health, addressing some of the most pressing challenges in modern science and medicine. This book explores a wide range of topics, including emerging strategies in drug design and discovery, AI-powered drug development, and digital transformation in the health sector. It offers a blend of theoretical perspectives and practical case studies on translational approaches in drug development, predictive analytics, and advances in drug synthesis and chemistry.
Jointly organized by the Global Health Techno Management Forum (GHTMF) and the Global Institute of Pharmaceutical Education and Research (GIPER), this symposium builds on the success of previous conferences, fostering collaboration among leading scientists, industry experts, and policymakers.
These proceedings are a vital resource for researchers, professionals, and policymakers aiming to accelerate the development of safer, more effective therapies. It serves as a roadmap for future innovations in pharmaceutical sciences, guiding the way towards a healthier, more equitable world.

Table of Contents:

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Innovations in Drug Design: Case Studies from Discovery to Development.- Development of Allosteric Inhibitors against Cyclin-Dependent Kinase 2 (CDK2).- Evaluation of 2-phenylthiazolidin-4-one analogues as inhibitors of the SARS-CoV-2 main protease.- Engineered Antibiotics: A Strategy to Combat Multi-Drug-Resistant Bacteria: A Review on Antibiotics Modification.- In silico studies of 1,2,4-triazole derivatives by targeting DHFR againsts staphylococcus aureus: Pharmacophore generation, Atom-based 3D-QSAR, Molecular docking and ADMET.- Rationale of Antifungal And Anti Bacterial Interventions Of Imidazole Derivatives.- Quantitative Structure Pharmacophore–Activity Relationship of Tricyclic Antidepressant (TCAs) Utilizing Distance–Based Features.- Computational Design of Pyrazole Derivatives for Management of Autoimmune Disease.- Designing, Synthesis and Characterization of Novel Heterocyclic Derivatives of-oxothiazolidine-3-carbonyl)-6- substituted-spiro[indoline-2,2'-thiazolidine]-3,4'-dione and -oxothiazolidine-3-carbonothioyl)-6- substituted-spiro [indoline-2,2'-thiazolidine]-3,4'-dione and their Bioevaluation.- Synthesis and Antimicrobial Evaluation of Novel dioxo spiro[indoline-3,2' thiazolidin]-3'-yl)thiourea and -dioxaspiro[indoline-3,2'-thiazolidin]-3'-yl)urea.