Geographical and Environmental Epidemiology
Methods for Small Area Studies
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Product details:
- Publisher OUP Oxford
- Date of Publication 25 July 1996
- ISBN 9780192622358
- Binding Paperback
- No. of pages404 pages
- Size 235x156x23 mm
- Weight 603 g
- Language English
- Illustrations numerous line figures and tables 0
Categories
Short description:
Now available in paperback, this book is the first to address both the theoretical and practical issues which arise when describing the geographical distribution of disease and investigating apparent disease clusters. Requirements in terms of population data, disease incidence, and mortality are considered and related to the scale at which a study is being carried out. Statistical methods are reviewed for large scale correlation studies, intermediate scale map smoothing exercises, and small scale clustering investigations. Problems of measuring environmental exposures at different scales are also reviewed.
These issues are then related to current practice via comprehensive set of case studies which include a large correlation study in China, clustering of asthma attacks, the Sellafield-leukaemia cluster, environmental clusters of mesothelioma in Turkey, and a multi-source study if cancer incidence around an incinerator.
Long description:
Now available in paperback, this book is the first to address both the theoretical and practical issues which arise when describing the geographical distribution of disease and investigating apparent disease clusters. Requirements in terms of population data, disease incidence, and mortality are considered and related to the scale at which a study is being carried out. Statistical methods are reviewed for large scale correlation studies, intermediate scale map smoothing exercises, and small scale clustering investigations. Problems of measuring environmental exposures at different scales are also reviewed.
These issues are then related to current practice via comprehensive set of case studies which include a large correlation study in China, clustering of asthma attacks, the Sellafield-leukaemia cluster, environmental clusters of mesothelioma in Turkey, and a multi-source study if cancer incidence around an incinerator.
well written and very readable. For a work with so many different contributors the continuity and uniformity of style is good. ... I regard this book as being of considerable use and interest to public health physicians ... For anyone considering carrying out an investigation of apparent disease clustering this book would be an invaluable source of help and information.
Table of Contents:
PART I: Introduction
Geographical epidemiology and ecological studies
Small-area studies: purpose and methods
Health and the environment: the significance of chemicals and radiation
PART II: Data, computational methods, and mapping
Mortality data
Cancer incidence data for adults
Cancer incidence data for children
Congenital anomalies
Specialized registers
Population counts in small areas
Use of routine data in studies of point sources of environmental pollution
Socio-economic confounding
Use of record linkage in small-area studies
Confidentiality
Practical approaches to disease mapping
Estimating environmental exposures
Mapping environmental exposure
PART III: Statistical methods
Statistical methods for geographical correlation studies
Bayesian methods for mapping disease risk
Statistical methods for analysing point-source exposures
Some comments on methods for investigating disease risk around a point source
Methods for the assessment of disease clusters
PART IV: Studies of health and the environment
Environmental epidemiology: a historical perspective: Guidelines for the investigation of clusters of adverse health events
Studies of disease clustering: problems of interpretation
PART V: Case studies
Childhood leukaemia around the Sellafield nuclear plant
The epidemic of respiratory cancer associated with erionite fibres in the Cappadocian region of Turkey
Soya bean as a risk factor for epidemic asthma
The Sevesco accident
Cancer of the larynx and lung near incinerators of waste solvents and oils in Britain
A study of geographical correlations in China
