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  • Explaining the Brain: Mechanisms and the Mosaic Unity of Neuroscience

    Explaining the Brain by Craver, Carl F.;

    Mechanisms and the Mosaic Unity of Neuroscience

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    Product details:

    • Publisher OUP Oxford
    • Date of Publication 7 June 2007

    • ISBN 9780199299317
    • Binding Hardback
    • No. of pages330 pages
    • Size 240x160x23 mm
    • Weight 633 g
    • Language English
    • Illustrations numerous figures
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    Short description:

    Carl Craver investigates what we are doing when we use neuroscience to explain what's going on in the brain. When does an explanation succeed and when does it fail? Craver offers explicit standards for successful explanation of the workings of the brain, on the basis of a systematic view about what neuroscientific explanations are: they are descriptions of mechanisms.

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    Long description:

    What distinguishes good explanations in neuroscience from bad? Carl F. Craver constructs and defends standards for evaluating neuroscientific explanations that are grounded in a systematic view of what neuroscientific explanations are: descriptions of multilevel mechanisms. In developing this approach, he draws on a wide range of examples in the history of neuroscience (e.g. Hodgkin and Huxleys model of the action potential and LTP as a putative explanation for different kinds of memory), as well as recent philosophical work on the nature of scientific explanation. Readers in neuroscience, psychology, the philosophy of mind, and the philosophy of science will find much to provoke and stimulate them in this book.

    This book should be of interest not just to those of us who care about philosophy of neuroscience, but also to philosophers of biology and philosophers of mind more generally. I expect it to shape debate for a long time to come.

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    Table of Contents:

    Preface
    Chapter 1. Introduction: Starting With Neuroscience
    Introduction
    Explanations in Neuroscience Describe Mechanisms.
    Explanations in Neuroscience are Multilevel
    Explanations in Neuroscience Integrate Multiple Fields
    Criteria of Adequacy for an Account of Explanation
    Chapter 2. Explanation and Causal Relevance
    Introduction
    How Calcium Explains Neurotransmitter Release
    Explanation and Representation
    The Covering-Law Model
    The Unification Model
    But What About the Hodgkin and Huxley Model?
    Conclusion
    Chapter 3. Causal Relevance and Manipulation
    Introduction
    The Mechanism of Long-Term Potentiation
    Causation as Transmission
    Transmission and Causal Relevance
    Omission and Prevention
    Causation and Mechanical Connection
    Manipulation and Causation
    Ideal Interventions
    Invariance, Fragility, and Contingency
    Manipulation and Criteria for Explanation
    Manipulation, Omission, and Prevention
    Conclusion
    Chapter 4. The Norms of Mechanistic Explanation
    Introduction
    Two Normative Distinctions
    Explaining the Action Potential
    The Explanandum Phenomenon
    Components
    Activities
    Organization
    Constitutive Relevance
    Relevance and the Boundaries of Mechanisms
    Interlevel Experiments and Constitutive Relevance
    Interference Experiments
    Stimulation Experiments
    Activation Experiments
    Constitutive Relevance as Mutual Manipulability
    Conclusion
    Chapter 5. A Field-Guide to Levels
    Introduction
    Levels of Spatial Memory
    A Field-Guide to Levels
    Levels of Science (Units and Products)
    Levels of Nature
    Causal Levels (Processing and Control)
    Levels of Size
    Levels of Composition
    Levels of Mereology
    Levels of Aggregativity
    Levels of Mere Material/Spatial Containment
    Levels of Mechanisms
    Conclusion
    Chapter 6 Nonfundamental Explanation
    Introduction
    Causal Relevance and Making a Difference
    Contrasts and Switch-Points
    Causal Powers at Higher Levels of Mechanisms
    Causal Relevance among Realized Properties
    Conclusion
    Chapter 7. The Mosaic Unity of Neuroscience
    Introduction
    Reduction and the History of Neuroscience
    LTP's Origins: Not a Top-Down Search but Intralevel Integration
    The Mechanistic Shift
    Mechanism as a Working Hypothesis
    Intralevel Integration and the Mosaic Unity of Neuroscience
    The Space of Possible Mechanisms
    Specific Constraints on the Space of Possible Mechanisms
    Componency Constraints
    Spatial Constraints
    Temporal Constraints
    Active Constraints
    Reduction and the Intralevel Integration of Fields
    Interlevel Integration and the Mosaic Unity of Neuroscience
    What is Interlevel Integration?
    Constraints on Interlevel Integration
    Accommodative Constraints
    Spatial and Temporal Interlevel Constraints
    Interlevel Manipulability Constraints
    Mosaic Interlevel Integration
    Conclusion: The Epistemic Function of the Mosaic Unity of Neuroscience

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