Essentials of Fat Grafting by Prantl, Lukas;

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Fat grafting has emerged as one of the most versatile and promising tools in modern Plastic and Aesthetic Surgery. Despite its widespread use, techniques and outcomes still vary significantly. Essentials of Fat Grafting bridges this gap with a unique, four-level structure that guides the reader from foundational techniques to advanced clinical applications—all grounded in evidence-based practice.

This comprehensive volume features contributions from over 60 internationally recognized experts, including Eckhard Alt, Geoffrey Gurtner, Amin Kalaaji, Roger Khouri, Lauren Kokai, Kotaro Yoshimura, Tsai-Ming Lin, Norbert Pallua, Rod Rohrich, Aris Sterodimas, Joris van Dongen and Alexis Verpaele. Their collective knowledge is distilled into practical checklists, decision-making algorithms, and step-by-step video tutorials.

The book provides detailed guidance on optimizing every stage of the fat grafting process—harvesting, processing, and reinjection—enabling clinicians to achieve superior and reproducible results. Professor Prantl presents his own innovations, while expert insights from a diverse range of specialists offer real-world solutions and recommendations for clinical implementation, particularly in the integration of fat and stem cell therapies.

Clear flowcharts and structured protocols ensure that even complex procedures become accessible, combining hands-on practicality with a solid scientific foundation.

This book is an essential resource for practitioners in Plastic and Aesthetic Surgery, Regenerative Medicine, Dermatology, Gynaecology, ENT, Urology, and Orthopaedics. It is designed to be both thought-provoking and practical—a trusted companion for daily clinical work.

A Pathway to Mastery:

· Level 1 – Beginner: Clear, easy-to-follow instructions and standard operating procedures for Cell-Enriched Lipotransfer (CELT), illustrated through flowcharts and high-definition videos.

· Level 2 – Advanced: In-depth exploration of key principles in fat harvesting, processing, and reinjection, presented by world-renowned experts.

· Level 3 – Expert: Comprehensive, translational insights covering fat grafting from laboratory research to clinical application.

· Level 4 – Specialist: Deep dives into subspecialties—ranging from facial rejuvenation and large-volume breast or gluteal augmentation to musculoskeletal, neurological, and exosome-based therapies.

Table of Contents:

Foreword.- Part I. Level 1: Standard evidence-based operating procedure: protocols for CELT and CELT PLUS.- 1. Standard evidence-based operating procedure: protocols for CELT and CELT PLUS. Part II. Level 2: Overview of key concepts in fat grafting.- 2. Comprehensive Principles of Large Volume Fat Transfer.- 3. Stromal Enriched Lipograft – SEL.- 4. Technical details of Reinjection.- 5. CELT and CELT plus.- Part III. Level 3: Extended overview for research and clinical application.- 6. Essentials. 7. How can I evaluate the quality and relevance of research on fat grafting for practical clinical use?.- Part IV. Level 4: Key concepts in adipose tissue research and engineering.- 8. Macroscopic anatomy of adipose tissue.- 9. Comparative histology of white and brown adipose tissue.- 10. Stromal vascular fraction (SVF)/ Adipose-Derived Stem Cells (ADSCs).- 11. Human Adipose derived Stem Cells (hADSCs) for therapeutical use.- 12. Role of the extracellular matrix of fat graft.- 13. Fundamentals of Adipose Tissue-Derived Exosome Research.- 14. Adipose Tissue Engineering.- 15. Experimental Models for Adipose Tissue Transplantation.- Part V. Level 4: Aging and pathological alterations of the adipose tissue.- 16. Role of Adipose tissue and Aging.- 17. Anti Aging Concepts.- 18. Age-releated changes of the adipose tissue in different body areas.- 19. Lipomatosis.- 20. Morbus Madelung.- 21. Lipedema.- Part VI. Level 4: Imaging adipose tissue.- 22. Digital Volumetry.- 23. MRI, Ultrasound, CT, PET.- Part VII. Level 4: Liposuction.- 24. Surgical anatomy for liposuction.- 25. Tumescent Anesthesia.- 26. Harvesting area in Liposuction.- 27. Aspiration devices and vacuum settings.- 28. Choosing the right cannula.- Part VIII. Level 4: Processing for clinical application and storage.- 29. Separation methods for lipoaspirate.- 30. Mechanical isolation methods of SVF.- 31. Cell Assisted Lipotransfer – CAL, Cytori, Ingeneron etc.- 32. Enhancing Fat Graft Outcomes: The Role of PRP and Vitamin C.- 33. Storage of Lipoaspirate, Adipose Stem Cells. Part IX. Level 4: Reinjection.- 34. Cutting-edge technology of 21st Century Micro-Autologous Fat Transplantation (MAFT) and the MAFT-GUN® in Plastic and Reconstructive Surgery.- 35. The ‘Micro-’ Concept in MAFT for Regenerative Medicine: Theory, Accessibility, Affordability, Indispensability, and Clinical Efficacy.- Part X. Level 4: Clinical applications of adipose tissue.- 36. Facial Rejuventation - relevant facial anatomy for fat grafting.- 37. Fat Augmentation for Contour Enhancement Technique (FACET) – bridging the gap between bench and bedside in facial fat grafting.- 38. Skin rejuvenation.- 39. Breast treatment with autologous fat grafting.- 40. Breast reconstruction.- 41. New Trends in Breast Augmentation with Fat Grafting: Implant Conversion with Fat and Hybrid Implant-Fat Breast Augmentation/Revision.- 42. Aesthetic breast treatment with BEAULI.- 43. Aesthetic breast treatment with Stromal enriched Fat Grafting for breast augmentation.- 44. Gluteal Augmentation with Fat:Patient Assessment, Operative Technique, and Safety Guidelines.- 45. Gluteal Augmentation.- 46. Indications for fat grafting in musculoskeletal disorders of the upper extremities.- 47. Autologous fat grafting in hand surgery.- 48. Intraarticular application of autologous fat grafting in the treatment of knee osteoarthritis.- 49. Wound Treatment.- 50. Nerve Regeneration.- 51. Scar treatment.- 52. Vocal cord.- 53. Incontinence.- 54. Erectile Dysfunction.- 55. Intravenous Application.- 56. Future developments.- Part XI. Level 4: Clinical Applications of Adipose-Derived Exosomes.- 57. Breast Cancer.- 58. Alzheimer. Part XII. Level 4: Safety aspects, complications, and risk factors.- 59. Oncological safety.- 60. Preoperative education and Aftercare and ultrasound diagnostics for lipofilling.