Dihydropyrimidinones as Potent Anticancer Agents by Ahmad Bhat, Mashooq; U Rehman, Muneeb; Verma, Amita;

Long description:

Dihydropyrimidinones as Potent Anticancer Agents gives readers a unique update on scientific knowledge, accomplishments and recent advances in the medicinal chemistry of dihydropyrimidinones in cancer treatment. Dihydropyrimidinones are known to be active scaffold and have been reported to show some exceptional results with regards to malignancies. With ever increasing knowledge and information about synthesis, pharmacology and other aspects of dihydropyrimidinones, there is need to document such information in one place. Since the field of medicinal chemistry is dynamic, with new emerging trends, it provides readily available updated information on chemistry and pharmacology aspects of dihydropyrimidinones in cancer.

This book covers everything about dihydropyrimidinones from synthesis, derivatives, mode of action and potential therapeutic targets. It will also provide insights about the clinical trials and way forward in cancer research of dihydropyrimidinones.

Table of Contents:

1. Introduction of Dihydropyrimidinones: Medicinal Chemistry Perspective
2. Synthetic strategies of dihydropyrimidinones.
3. Biological activities of dihydropyrimidinones.
4. Dihydropyrimidinones Scaffold and potential therapeutic targets
Dr. Amita Verma, Bioorganic and Medicinal Chemistry Research Laboratory
5. Dihydropyrimidinones Scaffold and potential anticancer targets.
6. Dihydropyrimidinones inhibits proliferation and tumour growth.
7. Novel Dihydropyrimidinones as potential cytotoxic agents in hepatocellular carcinomas
8. Applications of dihydropyrimidinone derivatives on blood cancer and colon cancer.
9. Therapeutic efficacy of dihydropyrimidinone in triple-negative breast cancer
10. Dihydropyrimidone derivaives with anticancer activity in clinical trials
Recent advances of Dihydropyrimidinone derivatives in cancer research