Application of Clay Polymer Nanocomposite as Drug Delivery Vehicle by Singhal, Rahul; Datta, Monika;

Long description:

In medical and pharmaceutical field, the necessity of tailor made drug delivery system has attained significant attention. This suggests that we should take a lead in the area of drug delivery systems. Clay is viable to drug delivery systems, and is expected to provide sustained release characteristics as well as enhanced mechanical properties owing to their layered structure. One of the clay that is montmorillonite act as an adsorbs dietary toxins, bacterial toxins associated with gastrointestinal disturbance, hydrogen ions in acidosis, and metabolic toxins such as steroidal metabolites associated with pregnancy. Similarly Clay-polymer nanocomposites based drug delivery system has the potential in oral sustained drug released in vitro condition at the physiologically required site which will in turn minimize the side effects specially in the treatment of cancer and is expected to provide better therapeutic efficacy in other medical areas. Thus by developing clay polymer nanocomposite systems, one can expect to combine the best properties of polymers as well as of the clay to obtain synergism. Moreover, it also reduces the cost of new drug development.