Vestibular Schwannomas by Lloyd, Simon; Pathmanaban, Omar; Evans, Gareth;

Hosszú leírás:

Vestibular Schwannomas covers multiple facets of vestibular schwannomas, including advancements in surgical techniques, radiological innovations, long-term patient outcomes, and implications for hearing preservation. It serves as a comprehensive guide for clinicians and researchers aiming to enhance diagnostic accuracy and therapeutic strategies in managing these complex tumors which are benign, slow-growing tumors that originate from the Schwann cells that line the vestibular nerve. They are the most prevalent neoplasms found in the cerebellopontine angle (CPA), the critical junction between the cerebellum and the brainstem.

Their incidence, clinical presentation, and impact on surrounding neurological structures make them a focal point of research and medical intervention. Understanding their etiology, diagnosis, and treatment options requires an interdisciplinary approach bridging neurology, otology, and radiology.

• Consolidates best practices on the diagnosis and treatment of vestibular schwannomas
• Includes both sporadic and neurofibromatosis type 2 vestibular schwannomas
• Covers stereotaxic radiosurgery and microsurgical resection
• Discusses molecular biology, histopathology, and genomics
• Presents rehabilitation for neurological deficits resulting from schwannomas and treatment

Tartalomjegyzék:

1. History of?vestibular schwannoma management

Section I. Basic Science
2. Applied anatomy in vestibular schwannoma
3. Molecular biology and disease models of vestibular schwannomas: State of the art
4. Pathology and tumor microenvironment of vestibular schwannoma
5. Genomics of vestibular schwannoma
6. Vestibular schwannomas: Key research questions and priorities

Section II. Assessment
7. Clinical evaluation and investigation of patients with a sporadic vestibular schwannoma
8. Clinical evaluation and investigation of vestibular schwannoma in NF2-related schwannomatosis
9. Vestibular schwannoma imaging and differential diagnosis
10. Clinical epidemiology of sporadic vestibular schwannomas
11. Clinical epidemiology of NF2-related schwannomatosis

Section III. Treatment
12. Surveillance management of vestibular schwannoma: present and future strategies
13. Medical therapy for vestibular schwannomas
14. Translabyrinthine approach to the cerebellopontine angle
15. Retrosigmoid approach to vestibular schwannoma
16. Middle fossa approach to vestibular schwannomas
17. The retrolabyrinthine approach
18. Endoscopic vestibular schwannoma surgery
19. Vestibular schwannoma microsurgical technique
20. Outcomes following vestibular schwannoma surgery
21. Salvage resection and radiosurgery following failed primary treatment of vestibular schwannomas
22. Hearing preservation surgery for vestibular schwannoma
23. Vestibular schwannoma, postsurgical complications
24. Anesthesia for excision of vestibular schwannoma

Section IV. Stereotactic radiosurgery for vestibular schwannomas
25. Gamma knife radiosurgery for vestibular schwannomas
26. LINAC stereotactic radiosurgery for vestibular schwannomas
27. Fractionated radiotherapy for vestibular schwannoma
28. Proton therapy for vestibular schwannomas

Section V. General Considerations
29. Decision making in sporadic VS
30. Decision making in NF2-related schwannomatosis
31. Management of vestibular schwannoma in the elderly
32. Subtotal versus total excision of vestibular schwannomas
33. Quality of life after treatment of vestibular schwannomas
34. The role of the clinical nurse specialist in managing vestibular schwannoma
35. Vestibular schwannoma: Global perspectives

Section VI. Rehabilitation
36. Secondary trigeminal neuralgia due to vestibular schwannoma
37. Hearing rehabilitation in patients with vestibular schwannomas
38. Prevention and rehabilitation of facial palsy in patients with vestibular schwannomas
39. Dizziness in vestibular schwannomas
40. Tinnitus and its management in patients with vestibular schwannoma