Stroke Genetics
Sorozatcím: Oxford Medical Publications;
-
10% KEDVEZMÉNY?
- A kedvezmény csak az 'Értesítés a kedvenc témákról' hírlevelünk címzettjeinek rendeléseire érvényes.
- Kiadói listaár GBP 307.50
-
146 908 Ft (139 912 Ft + 5% áfa)
Az ár azért becsült, mert a rendelés pillanatában nem lehet pontosan tudni, hogy a beérkezéskor milyen lesz a forint árfolyama az adott termék eredeti devizájához képest. Ha a forint romlana, kissé többet, ha javulna, kissé kevesebbet kell majd fizetnie.
- Kedvezmény(ek) 10% (cc. 14 691 Ft off)
- Kedvezményes ár 132 217 Ft (125 921 Ft + 5% áfa)
Iratkozzon fel most és részesüljön kedvezőbb árainkból!
Feliratkozom
146 908 Ft
Beszerezhetőség
Megrendelésre a kiadó utánnyomja a könyvet. Rendelhető, de a szokásosnál kicsit lassabban érkezik meg.
Why don't you give exact delivery time?
A beszerzés időigényét az eddigi tapasztalatokra alapozva adjuk meg. Azért becsült, mert a terméket külföldről hozzuk be, így a kiadó kiszolgálásának pillanatnyi gyorsaságától is függ. A megadottnál gyorsabb és lassabb szállítás is elképzelhető, de mindent megteszünk, hogy Ön a lehető leghamarabb jusson hozzá a termékhez.
A termék adatai:
- Kiadó OUP Oxford
- Megjelenés dátuma 2003. május 1.
- ISBN 9780198515869
- Kötéstípus Keménykötés
- Terjedelem362 oldal
- Méret 248x174x24 mm
- Súly 850 g
- Nyelv angol
- Illusztrációk numerous figures; tables; halftones and 4 pp colour plates 0
Kategóriák
Rövid leírás:
Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Research now suggests that genetic factors are important in stroke, often acting via interactions with conventional risk factors. However, an increasing number of single gene disorders causing stroke are being described. This book provides an up-to-date review of the field, suitable for clinicians active in the care of stroke patients, as well as both clinical and non-clinical researchers in the field of cerebrovascular disease.
TöbbHosszú leírás:
Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. An increasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke.
Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemic stroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence is reviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing a practical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.
The book is an essential purchase for physicians and neurologists with an interest in stroke, it covers areas of research not covered in detail by standard texts . . . Although intended for the 'stroke' clinician and the basic scientist entering the field, it is potentially of interest to a much wider audience. I would encourage neurology trainees to read the clinical chapters covering monogenic causes of stroke, intracerebral haemorrhage, aneurysm and arteriovenous malformation, and neurosurgery trainees to read that on the genetics of aneurysm. Medical students and housemen would profit from reading the editor's introductory and final chapters, and if all that is remembered is the table of relative risks for stroke and the importance of taking a systematic family history, two very helpful lessons will have been learnt. Neurology and medical school libraries should certainly obtain a copy.
Tartalomjegyzék:
Preface
An introduction to stroke
Genetic principles and techniques
Genetic epidemiology of stroke
Genetics of conventional stroke risk factors
Animal models of stroke: implications for genetic studies of human stroke
Monogenic causes of ischaemic stroke
Polygenic ischaemic stroke including new genetic and statistical approaches
Investigating the genetics of polygenic ischaemic stroke using intermediate phenotypes
Genetics of intracerebral haemorrhage
Genetics of subarachnoid haemorrhage and intracranial aneurysms
Familial cerebral arteriovenous malformations
The genetics of paediatric stroke
Investigating a patient with stroke for genetic causes
Useful web sites for stroke genetics
