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  • Risk Factors for Cerebrovascular Disease and Stroke

    Risk Factors for Cerebrovascular Disease and Stroke by Seshadri, Sudha; Debette, Stéphanie;

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    A termék adatai:

    • Kiadó OUP USA
    • Megjelenés dátuma 2016. április 21.

    • ISBN 9780199895847
    • Kötéstípus Keménykötés
    • Terjedelem488 oldal
    • Méret 160x236x30 mm
    • Súly 816 g
    • Nyelv angol
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    Rövid leírás:

    This book, by leading stroke researchers from Europe and North America, describes environmental and genetic risk factors for cerebrovascular disease. The section on genetics is exceptionally detailed and contemporaneous.

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    Hosszú leírás:

    Risk Factors for Cerebrovascular Disease and Stroke address the relationship of a wide variety of vascular risk factors in the spectrum of cerebrovascular diseases. An international group of professionals the forefront of research and education, provide their expertise about environmental and genetic determinants for cerebrovascular disease and stroke. The authors aim to provide information on developments of genetic, environmental and lifestyle-related risk factors of various subtypes of stroke, and MRI-markers of cerebrovascular disease.

    One in 2 men, and 1 in 3 women after the age of 40, will develop a stroke in their lifetime. The burden of cerebrovascular disease extends far beyond that of acute clinical events such as stroke, with "covert " vascular injury on brain MRI being highly prevalent in older community-dwelling persons. Therefore, improving our understanding of the risk factors for stroke and cerebrovascular disease is of paramount importance for improving prevention strategies. Secular trends in stroke epidemiology, risk factors, and intermediate markers (including carotid ultrasound, brain MRI and circulating biomarkers) are presented. Cutting edge information on genetic, environmental and lifestyle-related risk factors of various subtypes of stroke and MRI-markers of cerebrovascular diseases are displayed. This important book is an essential reference to physicians interested in more effective primary prevention of stroke.

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    Tartalomjegyzék:

    I. Introduction
    1. Epidemiology of stroke: incidence and prevalence, description of types and subtypes and their relative frequency, definition of risk factors
    II. Genetic risk factors
    2. Introduction to Genetic risk factors for cerebrovascular disease
    3. Monogenic forms of stroke and cerebrovascular disease
    4. Heritability of stroke
    5. Genetic determinants of ischemic stroke discovered through GWAS
    6. Genetic risk factors of intracerebral haemorrhage
    7. Relevance in stroke of genes associated with cardiovascular disease and risk factors\
    8. Genetics of Stroke associated with cervical artery dissections
    9. Genetics of cerebral venous thrombosis
    10. Genetic risk factors for brain MRI markers of cerebrovascular disease
    III. Environmental risk factors
    11. Overview of Environmental Risk Factors for Stroke
    12. Hypertension: the major risk factor for stroke
    13. Dyslipidemia and Risk of Stroke
    14. Metabolic risk factors: DM, obesity, metabolic syndrome
    15. Lifestyle factors and Risk of Stroke: smoking, alcohol, diet, physical activity, sleep
    16. Risk factors specific to young adults
    17. Sex-Specific Risk factors for Stroke in Women
    18. Migraine and Risk of Stroke and Cerebrovascular Disease
    19. Ethnic, Racial and Geographic Variations in Stroke Risk and Risk Factors
    IV. Integrative approach
    20. Intermediate markers: Carotid Atherosclerosis
    21. MRI-based Markers of Cerebrovascular Disease and the Risk of Stroke
    22. Circulating Biomarkers for Stroke
    23. Secular trends in Stroke Risk and Risk factors for Stroke

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