Oxford Textbook of Rheumatoid Arthritis by Scott, David L.; Galloway, James; Cope, Andrew;

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A termék adatai:

Kiadó OUP Oxford
Megjelenés dátuma 2020. szeptember 17.

ISBN 9780198831433
Kötéstípus Keménykötés
Terjedelem576 oldal
Méret 284x228x28 mm
Súly 1658 g
Nyelv angol

Kategóriák

Orthopédia, végtagbántalmak Fizioterápia, rehabilitáció, foglalkoztatási terápia Reumatológia

Rövid leírás:

The Oxford Textbook of Rheumatoid Arthritis covers all relevant aspects of the fisease, ranging from basic science, epidemiology, clinical and laboratory assessments, drug and non-drug treatments, and disease outcomes. Written by an international team of experts, it will be an invaluable resource for those involved with people with RA.

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Hosszú leírás:

This brand new textbook of rheumatoid arthritis (RA) is an important addition to the Oxford Textbooks in Rheumatology series, and provides a comprehensive overview of both the scientific and clinical aspects of the disease. Divided into eight sections - from the history, diagnosis, and epidemiology of the disease, through the pathogenesis, clinical presentation, and assessment to treatments and management strategies, both drug- and non-drug based - each chapter is written by leading clinicians and scientists in the field to deliver a contemporary view of RA.

During the past two decades there have been revolutionary changes in the understanding and management of rheumatoid arthritis, in particular the development of biological treatments. This has had wide-ranging effects on almost all aspects of treatment, from effectiveness and intensity to the nature and the cost. Providing a comprehensive account of the modern ideas about the disease, the Oxford Textbook of Rheumatoid Arthritis is a key new addition to the literature, with each chapter providing a detailed background, key recent advances, and areas of doubt and future developments.

Featuring over 170 photographs, radiological images, and clinical charts to aid both diagnosis and illustrate the rationale behind key scientific studies, this new title will prove an indispensable resource for specialist rheumatologists, trainees in rheumatology, and other members of the multi-disciplinary team.

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Tartalomjegyzék:

1. History, diagnosis, and epidemiology
The history of rheumatoid arthritis
Diagnosis
The descriptive epidemiology of rheumatoid arthritis
Modifiable and other risk factors for rheumatoid arthritis: a basis for prevention and better therapy
2. Pathogenesis
Genetics and epigenetics of rheumatoid arthritis
Dysregulation of synovial fibroblasts in rheumatoid arthritis
Autoantibodies in rheumatoid arthritis
Dendritic cells and T cells in rheumatoid arthritis
Mechanisms of bone and cartilage destruction
Cytokines and other mediators
3. Clinical presentation
Clinical features of rheumatoid arthritis
Pre-rheumatoid arthritis
Non-articular manifestations of rheumatoid arthritis
Comorbidity in rheumatoid arthritis
4. Disease assessment
Disease activity assessment in rheumatoid arthritis
Synovial biopsies
Radiography in rheumatoid arthritis
Ultrasound in rheumatoid arthritis
MRI in rheumatoid arthritis
5. Impact on life
Patient physical function in rheumatoid arthritis
Fatigue
Health economics
Rheumatoid arthritis and work
6. Non-drug treatments
Exercise
Foot health
Occupational therapy
Self-management: a patient's perspective
7. Drug treatments
Analgesics, Opioids, and NSAIDs
Glucocorticoids
Conventional disease modifying drugs
Tumour necrosis factor inhibitors
Interleukin-6 inhibitors
B-cell therapies
Biosimilars
Immunogenicity in response to biologic agents
The use of JAK inhibitors in the treatment of rheumatoid arthritis
Combination therapy in rheumatoid arthritis
Translation of new therapies: from bench to bedside
Adverse events in clinical studies in rheumatoid arthritis
8. Management and outcomes
Prevention of rheumatoid arthritis
Treatment targets and remission
Clinical outcomes
Clinical guidelines
European biologics registers
Voluntary patient registries