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    Beszerezhetőség

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    Why don't you give exact delivery time?

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    A termék adatai:

    • Kiadás sorszáma 2
    • Kiadó OUP USA
    • Megjelenés dátuma 2004. október 28.

    • ISBN 9780195152227
    • Kötéstípus Keménykötés
    • Terjedelem624 oldal
    • Méret 285x223x37 mm
    • Súly 1698 g
    • Nyelv angol
    • Illusztrációk numerous black & white photographs and line illlustrations
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    Rövid leírás:

    Neuroglia is the only comprehensive reference book on the basic biology and function of glial cells. It covers the entire field of glial research from the basic molecular and cellular properties of these cells to their involvement in neurological diseases including stroke, Alzheimer's Disease, and multiple sclerosis. This long-awaited second edition includes new chapters on transmitter release by extocytosis from glia, glia derived stem cells, glia synaptic transmission,
    glia and axon guidance, an entirely new section on mechanisms of glial injury, and several new chapters on the roles of glia in different diseases. It is an essential reference source for newcomers, including graduate students, to neuroanatomy, neurochemistry, neurophysiology, and molecular neurobiology. It
    is also a vital companion for established researchers in these fields as well as clinicians in neurology, neurosurgery, psychiatry, neuropathology and neuro-oncology.

    Több

    Hosszú leírás:

    Reflecting the dramatic advances in the field since the first edition was published 10 years ago, this book is the only comprehensive reference on glial cells. The majority of neuroscientists now acknowledge that neuroglia are elemental to most, if not all, brain functions. The second edition covers the entire field of glial research from the basic molecular and cellular structure of these cells to their involvement in neurological diseases including stroke, Alzheimer's disease and
    multiple sclerosis. It includes new chapters on transmitter release by exocytosis from glia, glia derived stem cells, glia and synaptic transmission, glia and axon guidance, mechanisms of glial injury, and the roles of glia in different diseases.

    The new edition was written with both students and experts in mind. It provides a basic introduction to the entire range of glial topics and detailed information with critical assessment of the research literature. Neuroscience textbooks focus on the properties of neurons, whereas this book fills the information void about the brain's other cells. This book is an essential reference source for newcomers, including graduate students, to neuroanatomy, neurochemistry, neurophysiology and
    molecular neurobiology. It is also a vital companion for established researchers in these fields as well as clinicians in neurology, neurosurgery, psychiatry, neuropathology and neuro-oncology.

    The book is unquestionably an authoritative and comprehensive compilation of the various aspects on neuroglia.

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    Tartalomjegyzék:

    The Concept of neuroglia: a historical perspective
    Part 1: Properties of neuroglial cells
    Morphology and ultrastructure of glial cells
    Astrocytes and ependymal glia
    Structure and function of oligodentrocytes
    Schwann cells and myelin
    Microglial cells
    Lineage
    Lineages of astrocytes and oligodendrocytes
    The Schwann cell lineage
    The role of neurogenic astroglial cells in the developing and adult central nervous system
    Physiological and biochemical properties
    Voltage-activated ion channels in glial cells
    Receptors for neurotransmitters and hormones
    Cytokine and chemokine receptors and signalling
    Mechanisms of solute transport in glia
    Gap junctions and hemichannels
    Quantal release of transmitter: not only from neurons but from astrocytes as well?
    Enzymes of carbohydrate and energy metabolism
    Second messenger systems
    Intracellular calcium control mechanisms in glia
    Cytoskeletal proteins in astroglia
    Part 2: Functions of neuroglial cells
    Myelin
    Molecular biology of myelination
    Factors controlling myelin formation
    Myelin function and saltatory conduction
    Immune function
    Cytokine production
    Interaction of glial cells with monocytes
    Antigen processing, presentation, and T cell interaction
    Blood-brain-barrier
    The role of glia in the formation and function of the blood-brain-barrier
    Influence on neurons
    Extracellular potassium and pH: homeostasis and signalling
    Astrocyte neurotransmitter uptake
    Glia and synaptic transmission
    The central role of astrocytes in neuroenergetics
    Growth factors for neurons provided by macroglial cells
    Development
    Radial glial cells: scaffolding for cortical development and evolution
    Axon guidance
    Part 3: Disease and neuroglial cells
    Mechanisms of glial injury
    Astrocyte injury
    Oligodendrocyte and Schwann cell injury
    Response of microglia to brain injury
    Recovery of neural function
    Axonal regeneration in the peripheral nervous system of mammals
    Axonal regeneration in the central nervous system of mammals
    Transplantation of myelin-forming cells
    Diseases
    Multiple Sclerosis
    Human immunodeficiency virus infection of the central nervous system
    Focal cerebral ischemia: the multifaceted role of glial cells
    Gliomas
    Neurological mouse mutants: a molecular-genetic analysis of myelin proteins
    Astrocytic swelling in neuropathology
    The activation of microglia as an early sign of disease progression in Alzheimer's disease
    Peripheral neuropathy and the Schwann cell
    Reaction of glial cells in infectious disorders of the central nervous system

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