Mosaic of Autoimmunity by Perricone, Carlo; Shoenfeld, Yehuda;

The Novel Factors of Autoimmune Diseases

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A termék adatai:

Kiadó Elsevier Science
Megjelenés dátuma 2019. február 13.

ISBN 9780128143070
Kötéstípus Puhakötés
Terjedelem728 oldal
Méret 276x215 mm
Súly 1970 g
Nyelv angol

Kategóriák

Immunológia, allergológia

Hosszú leírás:

The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases.

An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis.

Több

Tartalomjegyzék:

Introduction
1. The history of the mosaic of autoimmunity
2. The novel aspects on the mosaic of autoimmunity?

Cellular and molecular mechanisms
3. B cells
4. B-reg?
5. T cells
6. Th17 cells
7. NK cells
8. Dendritic cells
9. Complement
10. Autoantibodies
11. Anti-DSF70
12. Genetic
13. Epigenetic
14. Post-translational modifications
15. Cytokines and chemokines
16. Autophagy
17. Diagnostic: laboratory?
18. Diagnostic: imaging

The classical factors associated with autoimmunity
19. Hormones
20. Microbiota
21. Infections: Viruses and bacteria

The novel environmental factors associated with autoimmunity
22. Geo-epidemiology
23. Seasonality
24. UV
25. Vitamin D
26. Vitamin D pregnancy and autoimmunity
27. Smell
28. Breast feeding
29. Vaccines
30. Silicone
31. Diet: spicy food and fatty acids
32. Diet: gluten
33. Psychological stress
34. Coffee
35. Obesity
36. Physical activity
37. Smoke
38. Cannabis
39. Bisphenol
40. Prolactin

Peculiar aspects
41. Cancer
42. Paraneoplastic syndromes

Classical autoimmune diseases
43. SLE
44. APS
45. CAPS
46. RA and inflammatory arthritides
47. PsA and Spondyloarthropathies
48. MS, MG and other neurological disorders
49. Systemic slcerosis
50. Sjogren
51. ASIA syndrome
52. Reproductive failure
53. Accelerated atherosclerosis
54. New autoimmune diseases

Treatment of autoimmune diseases
55. Neuroimmunology
56. Vasculitis
57. Personalized Medicine
58. Biologics and Biosimilars
59. Small molecules
60. Helminthes
61. Novel therapies and IVIg
62. Autoimmune and allergic disease
63. EBV Molecular Diagnosis
64. Statin and myositis
65. Autoimmunity and primary immunodeficiency