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  • Landmark Papers in Pain: Seminal Papers in Pain with Expert Commentaries

    Landmark Papers in Pain by Farquhar-Smith, Paul; Beaulieu, Pierre; Jagger, Sian;

    Seminal Papers in Pain with Expert Commentaries

    Sorozatcím: Landmark Papers In;

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    A termék adatai:

    • Kiadó Oxford University Press
    • Megjelenés dátuma 2018. június 1.

    • ISBN 9780198737490
    • Kötéstípus Keménykötés
    • Terjedelem320 oldal
    • Méret 246x171 mm
    • Nyelv angol
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    Kategóriák

    Rövid leírás:

    Landmark Papers is a definite collection of over 80 seminal papers that revolutionised Pain Medicine. Detailed commentaries by leading specialists highlight the significance of literature, which stimulated a paradigm shift in therapeutic strategy, or acted as a catalyst for improved clinical methods in the field.

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    Hosszú leírás:

    Pain Medicine, a relatively new specialty, has proven increasingly relevant to medical practitioners in every field. The specialism of pain has emerged over the past 50 years, largely due to the persistence of experts and new medical evidence that points to its necessity. Today, it is a distinct and integral part of global medical practice.

    Landmark Papers in Pain offers a comprehensive inventory of over 80 key studies in pain medicine from the last 100 years. Each paper is accompanied by a concise commentary on the significance of the original findings written by an expert in pain. The reviews discuss how the paper influenced the development of the speciality, and how the findings have advanced our global comprehension of pain. Together, the selected papers and reviews chart the growth of an embryonic field into the
    modern speciality of pain medicine.

    Complied by leading specialists in the field, the papers included in this book are significant for any student, researcher, clinical practitioner, or medical historian interested in pain medicine. Organised into eight distinct topics and cross-referenced by topics and author of original paper, the book is comprehensive in its coverage and easy to use. A review of the contemporary and historical research that shaped the speciality of pain, Landmark Papers in Pain is essential reading
    for all medical practitioners with an interest in pain medicine.

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    Tartalomjegyzék:

    Section 1: Historical
    Local anaesthetic substitutes for cocaine
    Innovative concepts in pain management
    Explaining reflex sympathetic dystrophy
    The rediscovery of paracetamol
    The pharmacology of placebos
    Understanding the responsiveness of c-fibres
    A new theory of pain
    Three determinants of pain
    Purinergic nerves: a new type of nerve
    Genetic differences in opiate receptors
    Endogenous opioids in placebo-induced analgesia
    Ethical pain experimentation in conscious animals
    Local anaesthetic creams
    The backpain revolution
    The mechanism of aspirin
    Mechanisms of visceral pain in IBS
    The effects of morphine on the central nervous system
    Opiods in palliative care
    Endogenous opiods in the central nervous system
    Spinal opioid analgesia in the rat
    Section 2: Firsts
    The key role of NGF in inflammatory pain processing
    Mapping of neurotrophin receptors on adult sensory neurons
    Plasticity in somatic receptive fields after nerve injury
    Peripheral neural mechanisms of cutaneous hyperalesia and heat pain
    The Cloning and Characterization of CB1
    Deorphanisation of ORL-1/LC132 by reverse pharmacology in two landmark studies
    The capsaicin receptor
    Vanilloid receptor 1 in inflammatory thermal hyperalgesia
    A signature of pain in the brain
    Cytokines as central to peripheral sensitisation and hyperalgesia
    Endogenous opioids mediate stress-induced analgesia
    The first crystal structure of an iGluR ligand-binding core
    Control of pain initiation by endogenous cannabinoids
    Peripheral Analgesia involves Cannabinoid Receptors
    Glia: a new pain target
    The challenges of animal models of pain
    Mechanisms of bone cancer pain
    Molecular Structure of the Mu-Opioid Receptor
    Milestone Effect of DNIC in our Understanding of Pain
    Original description of central sensitisation
    Molecular basis for Placebo effect
    Section 3: Science
    Early discussions on an mechansitic approach to pain
    Plasticity: a kew concept in pain
    The importance of descending modulatory pain systems
    Nocebo and its importance in clinical practice
    Mechanisms of Action of Acetaminophen for Pain Treatment
    Making the link from central sensitization to clincal pai
    Section 4: Clinical
    Proof of concept: epidural morphine
    The Definition of Fibromyalgia
    The advent of PCA for post operative analgesia
    Undertreatment of pain with metastatic cancer
    Faces scales in paediatric pain assessment
    Epidural block and phantom limb pain
    Clarifying the concept of Breakthrough pain
    Section 5: Mechanisms
    Paediatric pain epidemiology
    Recognising the importance of HIV disease and pain
    The additive analgesia of adrenaline in epidural blockade
    The additive analgesia of adrenaline in epidural blockade
    What is the clinical relevance of the Likert scale for pain?
    Post operaitve pain: assessing the standards
    Opioid induced hyperalgesia
    CRPS epidemiology
    Seminal paper on epidemiology of cancer pain
    Endoscopic ultrasounfd guided coeliac plexus block
    Section 6: Neuropathic
    Autotomy: an early neuropathic pain model
    Risk factors for post amputation pain
    Chronic constriction injury (CCI) model of neuropathic pain
    Antineuropathic medication combinatoin therapy
    RCT evidence for gabapentin in post herpetic neuralgia
    Idenitifcation of the target of gabapentinoid action in neuroapthic pain
    Recognition of the importance of Neuropathic pain epidermiology
    Botox analgesia for neuropathic pain
    DNIC and prediction of chronic post surgical pain
    Pregabalin in the reduction of chronic post knee surgery chronic pain
    Multidisciplinary Cognitive Behavioural Treatment for Chronic Pain
    Disability in Chronic Low Back Pain
    Section 7: Psychosocial
    The Understanding of Social Effects in Pain
    Section 8: Genetics
    Congenital insensitivity to pain
    Polymorphic CYP2D6 as the Responsible Enzyme of Activation
    COMT genotypes in pain responses
    The link between NaV1.7 mutation and erythromelelgia
    COMT and morphine use in cancer pain
    Pinoeering use of gene thearpy for pain

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