Instant Notes in Immunology by Lydyard, Peter M; Porakishvili, Nina; Cole, Michael F;

Rövid leírás:

This fourth edition, is the perfect text for science undergraduates and medical students looking for a concise introduction to the subject, or a study guide to use before examinations. Thoroughly updated in all areas, especially in mucosal immunity, regulation of the immune response and cancer immunotherapy.

Hosszú leírás:

Instant Notes in Immunology, Fourth Edition, is the perfect text for science undergraduates and medical students looking for a concise introduction to the subject or a study guide to use before examinations. This edition has been thoroughly updated in all areas, especially in mucosal immunity, regulation of the immune response and cancer immunotherapy. Each topic begins with a summary of essential facts, which serves as an ideal revision checklist, followed by a description of the subject that focuses on core information along with clear, simple diagrams that are easy for students to understand and recall in essays and exams.

• Beautifully illustrated to elucidate key concepts and mechanisms








• Topics listed under basic and clinical immunology








• New to this edition, the page design and many of the key diagrams and photos are now in full color








• Each subsection begins with a concise list of key concepts








• A free-to-access companion website hosts a wealth of resources, including interactive questions, as well as additional content to supplement that provided in the book

Tartalomjegyzék:

Preface. SECTION A OVERVIEW OF THE IMMUNE SYSTEM. A1 The Need. A2 External Defenses. A3 Immune Defense. A4 Antigens. A5 Hematopoiesis—Development of Blood Cells. SECTION B CELLS AND MOLECULES OF THE INNATE IMMUNE SYSTEM. B1 Cells of the Innate Immune System. B2 Molecules of the Innate Immune System. B3 Recognition of Microbes by the Innate Immune System. B4 Innate Immunity and Inflammation. SECTION C THE ADAPTIVE IMMUNE SYSTEM. C1 Lymphocytes. C2 Lymphoid Organs and Tissues. C3 Mucosa-Associated Lymphoid Tissues. C4 Lymphocyte Traffic and Recirculation. C5 Adaptive Immunity in the Neonate and Early Life. SECTION D ANTIBODIES. D1 Antibody Structure. D2 Antibody Classes. D3 Generation of Diversity. D4 Allotypes and Idiotypes. D5 Antigen–Antibody Complexes (Immune Complexes). D6 Immunoassay. D7 Antibody Functions. SECTION E THE T-CELL RESPONSES—CELL-MEDIATED IMMUNITY. E1 The Role of T Cells in Immune Responses. E2 T-Cell Recognition of Antigen. E3 Shaping the T-Cell Repertoire. E4 T-Cell Activation. E5 Clonal Expansion and Development of Memory and Effector Function. SECTION F THE ANTIBODY RESPONSE. F1 The B-Cell Receptor Complex and Co-Receptors. F2 B-Cell Activation and Signaling. F3 The Cellular Basis of the Antibody Response. F4 Antibody Responses in Different Tissues. SECTION G REGULATION OF THE IMMUNE RESPONSE. G1 Overview. G2 Regulation of Innate and Adaptive Immune Systems. G3 Tolerance to Self-Antigens. G4 Neuroendocrine Regulation of Immune Responses. G5 Regulation of the Immune Response: Environmental Mechanisms. SECTION H IMMUNITY TO INFECTION. H1 The Microbial Cosmos. H2 Immunity to Different Organisms. H3 Pathogen Defense Strategies. H4 Pathophysiology of Infectious Diseases. SECTION I VACCINATION. I1 Principles of Vaccination. I2 Immunization. I3 Antigen Preparations. I4 Vaccines to Pathogens and Tumors. SECTION J IMMUNODEFICIENCY—WHEN THE IMMUNE SYSTEM FAILS. J1 Deficiencies in the Immune System. J2 Primary Immunodeficiency. J3 Secondary (Acquired) Immunodeficiency. J4 Diagnosis and Treatment of Immunodeficiency. SECTION K HYPERSENSITIVITY—WHEN THE IMMUNE SYSTEM MISBEHAVES. K1 Definition and Classification. K2 IgE-Mediated (Type I) Hypersensitivity: Allergy. K3 IgG- and IgM-Mediated (Type II) Hypersensitivity. K4 Immune-Complex-Mediated (Type III) Hypersensitivity. K5 Delayed (Type IV) Hypersensitivity. SECTION L AUTOIMMUNITY AND AUTOIMMUNE DISEASES. L1 The Spectrum and Prevalence of Autoimmunity. L2 Factors Contributing to the Development of Autoimmune Disease. L3 Autoimmune Diseases: Potential Mechanisms for the Breakdown of Self-Tolerance. L4 Disease Pathogenesis—Effector Mechanisms. L5 Diagnosis and Treatment of Autoimmune Disease. SECTION M TRANSPLANT REJECTION. M1 The Transplantation Problem. M2 Transplantation Antigens. M3 Rejection Mechanisms. M4 Prevention of Graft Rejection. SECTION N TUMOR IMMUNOLOGY. N1 Origin and Host Defense against Tumors. N2 Tumor Antigens. N3 Immune Responses to Tumors. N4 Immunodiagnosis. N5 Cytokine and Cellular Immunotherapy of Tumors. N6 Immunotherapy of Tumors with Antibodies. N7 Tumor Vaccines. SECTION O GENDER AND THE IMMUNE SYSTEM. O1 Overview. O2 Immune Cells and Molecules Associated with the Reproductive Tracts. O3 Functional Effects of Sex Hormones on the Immune System. SECTION P AGING AND THE IMMUNE SYSTEM (IMMUNOSENE SCENCE). P1 Overview. P2 Changes in Lymphoid Tissues and Lymphocytes with Age. P3 The Effects of Aging on the Innate and Adaptive Immune Systems. P4 Other Factors Contributing to Immunosenescence in the Aged. SECTION Q IMMUNOTHERAPY. Q1 Cytokine-, Antibody-, and Cell-Mediated Immunotherapy. Q2 Cytokine-Mediated Immunotherapy. Q3 Antibody-Mediated Immunotherapy of Non-Cancer Diseases. Q4 Cellular Immunotherapy of Non-Cancer Diseases. Further Reading. Abbreviations. Glossary. Index.