Hosszú leírás:

The Handbook of Proteolytic Enzymes, Fourth Edition is the latest release in this esteemed publication that stands as the most comprehensive work in applied enzymology and biocatalysis since the first edition published in 1998. Extensively updated, the new edition is an essential reference for biochemists, biotechnologists, and molecular biologists across academia and industry. Edited by world-renowned experts in the field, and with five volumes available for individual sale, this work provides detailed information on all known proteolytic enzymes researched to-date, with expanded coverage of metallopeptidases, cysteine peptidases, serine and threonine peptidases, aspartic and glutamic peptidases, and inhibitors of proteolytic enzymes.

This volume includes over 400 chapters on known serine and threonine peptidases, including their name, history, activity and specificity, structural chemistry, preparation, biological aspects, and distinguishing features, with 2D and 3D structures of peptidases in color, extensive references, and links to PubMed and MEROPS databases.

• Provides the only comprehensive book on serine and threonine peptidases, with over 400 peptides included
• Written by experts in their field, including updates on proteolytic enzymes from all groups of living organisms and viruses, and some that are major targets of pharmaceutical research
• Presents a fully searchable text, with 2D and 3D structures of peptidases in color and links to PubMed and MEROPS databases
• Details the latest proteotases used in therapeutic research and discusses recent drug trials

Tartalomjegyzék:

SERINE AND THREONINE PEPTIDASES (Volume 2)

New chapters
Transmembrane peptidase, serine 4
Mesotrypsin
Kallikrein-related peptidase 6
Arginyl peptidase
HtrA peptidase (Helicobacter)
HtrA peptidase (Borrelia burgdorferi)
Zika virus NS2B-NS3 peptidase
Keratinase K1 (Stenotrophomonas maltophilia)
Mycosin-1
Dipeptidylpeptidase homologue DPP6
ClpP1 peptidase (Streptomyces)
ClpP2 peptidase (Streptomyces)

Major revisions
Chymotrypsin A (cattle-type)
Granzyme B (Homo sapiens-type)
Tryptase beta
Kallikrein-related peptidase 3
Kallikrein-related peptidase 5
Kallikrein-related peptidase 7
Corin
Factor VII-activating peptidase
Trypsin 1
Cationic trypsin (Homo sapiens-type)
Elastase-2
Cathepsin G
Myeloblastin
Chymase (Homo sapiens-type)
Prostasin
Mesotrypsin
Coagulation factor VIIa
Coagulation factor IXa
Coagulation factor Xa
Coagulation factor XIa
Coagulation factor XIIa
Thrombin
Plasma kallikrein
Urokinase-type plasminogen activator
t-Plasminogen activator
Plasmin
Hepsin
Epitheliasin
Matriptase
Matriptase-2
HtrA1 peptidase (Homo sapiens-type)
HtrA2 peptidase
Flavivirin
Hepacivirin
Bacterial proteasome, beta component
Proteasome subunit beta1c
Proteasome subunit beta2c
Proteasome subunit beta5c
Proteasome subunit beta1i
Proteasome subunit beta5i
Taspase-1
Subtilisin Carlsberg
PfSUB1 peptidase
PCSK1 peptidase
PCSK9 peptidase
Site-1 peptidase
Furin
Tripeptidyl-peptidase I
Prolyl oligopeptidase
Dipeptidyl-peptidase IV (eukaryote)
Fibroblast activation protein alpha subunit
Dipeptidyl-peptidase 9
Serine carboxypeptidase A
Lysosomal Pro-Xaa carboxypeptidase
Signal peptidase I
Lon-A peptidase
PIM1 peptidase
Peptidase Clp (type 1)