Features, Transmission, Detection, and Case Studies in COVID-19

Preface I. SARS-CoV-2 and COVID-19: Introductory chapters and setting the scene 1. Coronavirus Disease 2019 (COVID-19) pandemic in context: Systemic effects 2. Early warning signals of SARS-CoV-2 infection 3. Mobile phones and their use to study dynamics of COVID19 pandemic II. Structure, transmission and avoidance 4. Cis regulatory elements: A novel communication route between the host cell and SARS-CoV-2 genome 5. SARS-CoV-2 ORF8: Structure, Evolution, Molecular Function, and Its Contribution to the Pathogenicity of the Virus 6. SARS-CoV-2 Spike Protein Binding Ligands and Its Application in COVID-19 Therapeutics. 7. Autophagy and COVID-19 8. The Omicron variant of SARS-CoV-2 9. Monitoring SARS-CoV-2 spread in hospitals 10. Computational analysis of mutations in SARS-CoV-2 variants spike protein and protein interactions 11. Airborne transmission of SARS-CoV-2 12. Reducing transmission of SARS-CoV-2 with face masks: its potential protective effects 13. Digital twin of ventilation system against COVID-19 transmission and infection risk 14. SARS-CoV-2 infection and transmission in pets 15. SARS-CoV-2 transmission in dental practices 16. SARS-CoV-2 compared with influenza and respiratory syncytial virus in terms of vertical transmission 17. Reducing droplets and aerosols in the surgical setting and applications to the COVID-19 pandemic 18. SARS-CoV motion dynamics: linking in droplet size 19. Ventilation and airborne particles in classrooms: implications for the COVID-19 pandemic 20. Environmental SARS-CoV-2 transmission and e-cigarette aerosols III. Impact and Effects 21. The Impact of COVID-19 on First Responders 22. COVID-19 and suspected drug-induced liver injury 23. Pulmonary fibrosis in COVID-19 24. The effect of SARS-CoV-2 infection on cancer: clinical correlation and potential pathological mechanism 25. Severe SARS-CoV-2, platelet-endothelium interactions and cardiovascular damage 26. Cardio-metabolic Syndrome and COVID-19: Pathophysiological aspects 27. COVID-19 and Type I and II diabetes: an overview 28. COVID-19 and older adults: an overview 29. COVID-19 and male fertility: an overview 30. COVID-19 and obesity: an overview IV. Treatments, strategies and vaccines 31. COVID-19 vaccines and their impact: an overview 32. Exploring the Promise of COVID-19 Vaccines: A Review of Preclinical Studies 33. Drugs actively being investigated for use in COVID-19 34. The biology of neutralizing antibody cocktail therapy with REGN-COV 35. The intensive care unit and percutaneous tracheostomy in COVID-19 36. Cardiac effects of drugs and vaccines used to treat or prevent COVID -19 37. COVID-19 Pandemic and isolation: impact on sleep 38. Strategies in the COVID-19 pandemic: Disinfection of gloved hands 39. In silico studies on established antivirals on SARS-CoV-2 RNA-dependent RNA polymerase 40. The COVID-19 cytokine storm and its immunomodulatory treatment 41. Safety and efficacy of nebulization for reducing the intensity of viral load and clinical manifestations in patients with COVID-19 V. Detection and biomarkers 42. Bronchoalveolar lavage (BAL) and use in detection of SARS-CoV-2 43. SARS-CoV-2 testing and vaccination among people who use drugs 44. Homocysteine as a biomarker in COVID-19 45. Assessment of smell and taste in COVID-19 46. S-gene analysis: RT-PCR and Sanger sequencing applied to SARS-CoV-2 virus 47. False-negatives in screening for SARS-CoV-2 48. Sample pooling and SARS-CoV-2 assays 49. Biomarkers of Invasive Mechanical Ventilation in Obesity and Metabolic Syndrome VI. Case studies with mini review 50. Hypoxia and heart-lung interactions in COVID-19: The significance of right heart dysfunction and shunt 51. CASE STUDY: Neurology, ulnar nerve dysfunction and COVID-19 52. CASE STUDY: Acute kidney injury and COVID-19 53. CASE STUDY: The detection and treatment of a pneumothorax in a patient with Coronavirus Disease 2019 pneumonia 54. CASE STUDY: Conducting ventilation and airflow studies where airborne outbreaks of SARS-CoV-2 have possibly occurred: preventing recurrence VII. Resources 55. Recommended Resources for the Features, Transmission and Detection of Coronavirus Disease 2019 (COVID-19)