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    Emergence of In Vitro 3D Systems to Model Human Malaria

    Emergence of In Vitro 3D Systems to Model Human Malaria by Kulkeaw, Kasem;

      • 20% KEDVEZMÉNY?

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      • Kiadói listaár EUR 139.09
      • Az ár azért becsült, mert a rendelés pillanatában nem lehet pontosan tudni, hogy a beérkezéskor milyen lesz a forint árfolyama az adott termék eredeti devizájához képest. Ha a forint romlana, kissé többet, ha javulna, kissé kevesebbet kell majd fizetnie.

        59 001 Ft (56 192 Ft + 5% áfa)
      • Kedvezmény(ek) 20% (cc. 11 800 Ft off)
      • Discounted price 47 201 Ft (44 954 Ft + 5% áfa)

    Beszerezhetőség

    Becsült beszerzési idő: A Prosperónál jelenleg nincsen raktáron, de a kiadónál igen. Beszerzés kb. 3-5 hét..
    A Prosperónál jelenleg nincsen raktáron.

    Why don't you give exact delivery time?

    A beszerzés időigényét az eddigi tapasztalatokra alapozva adjuk meg. Azért becsült, mert a terméket külföldről hozzuk be, így a kiadó kiszolgálásának pillanatnyi gyorsaságától is függ. A megadottnál gyorsabb és lassabb szállítás is elképzelhető, de mindent megteszünk, hogy Ön a lehető leghamarabb jusson hozzá a termékhez.

    A termék adatai:

    • Kiadás sorszáma 2023
    • Kiadó Springer
    • Megjelenés dátuma 2023. május 30.
    • Kötetek száma 1 pieces, Book

    • ISBN 9789819906901
    • Kötéstípus Keménykötés
    • Terjedelem94 oldal
    • Méret 235x155 mm
    • Súly 336 g
    • Nyelv angol
    • Illusztrációk 1 Illustrations, black & white
    • 508

    Kategóriák

    Rövid leírás:

    This book illustrates the importance and advances of the disease model for malaria, a globally affected public health problem. This book provides comprehensive information on the malaria biology in a liver and all in vitro platforms for liver-stage malaria, including principles, protocols, applications for disease modeling and drug screening, and their limitations. The initial chapter describes the basis of stem cells in liver generation during development and in adults. The subsequent chapters highlight recent and emerging advances in liver organoid and liver-on-a-chip in modeling malaria. The book presents current protocols and methods to generate liver organoid and liver-on-a-chip together with their advantages and limitations. Toward the end, the book examines the humanized mouse model of liver-stage malaria using ectopic artificial livers regarding novel readout modalities. The recent advancement and challenges in combining liver-on-a-chip technology with biosensors are highlighted for assessing hepatocyte development viability and functions. The book elucidates the potential of these 3D models to understand the biological complexity of cellular and molecular mechanisms involved in Plasmodium development in the liver, toolboxes to investigate parasite deployment in the 3D models, and to implement in drug discovery. Finally, the book discusses the future directions and challenges in the applications of liver organoids and liver on-chip in the biology of live-stage malaria. This book is helpful for researchers and scientists in the field of parasitology, cell biology, tissue engineering, and pharmacology.

    Több

    Hosszú leírás:

    This book illustrates the importance and advances of the disease model for malaria, a globally affected public health problem. This book provides comprehensive information on the malaria biology in a liver and all in vitro platforms for liver-stage malaria, including principles, protocols, applications for disease modeling and drug screening, and their limitations. The initial chapter describes the basis of stem cells in liver generation during development and in adults. The subsequent chapters highlight recent and emerging advances in liver organoid and liver-on-a-chip in modeling malaria. The book presents current protocols and methods to generate liver organoid and liver-on-a-chip together with their advantages and limitations. Toward the end, the book examines the humanized mouse model of liver-stage malaria using ectopic artificial livers regarding novel readout modalities. The recent advancement and challenges in combining liver-on-a-chip technology with biosensors are highlighted for assessing hepatocyte development viability and functions. The book elucidates the potential of these 3D models to understand the biological complexity of cellular and molecular mechanisms involved in Plasmodium development in the liver, toolboxes to investigate parasite deployment in the 3D models, and to implement in drug discovery. Finally, the book discusses the future directions and challenges in the applications of liver organoids and liver on-chip in the biology of live-stage malaria. This book is helpful for researchers and scientists in the field of parasitology, cell biology, tissue engineering, and pharmacology.?

    Több

    Tartalomjegyzék:

    Chapter 1_Introduction to malaria biology in a liver.- Chapter 2_Modeling a liver-stage malaria.- Chapter 3_Liver organoid and liver-on-a-chip.- Chapter 4_Generation of liver organoid.- Chapter 5_Generation of liver-on-a-chip.- Chapter 6_The use of 3D in vitro systems to model human malaria.



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