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  • Durability and Reliability of Medical Polymers

    Durability and Reliability of Medical Polymers by Jenkins, Mike; Stamboulis, Artemis;

    Sorozatcím: Woodhead Publishing Series in Biomaterials;

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    • Kiadó Elsevier Science
    • Megjelenés dátuma 2018. október 30.

    • ISBN 9780081016558
    • Kötéstípus Puhakötés
    • Terjedelem296 oldal
    • Méret 234x156 mm
    • Nyelv angol
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    Hosszú leírás:

    Given the widespread use of polymers in medical devices, the durability and reliability of this material in use is an area of critical importance. Durability and reliability of medical polymers reviews the performance of both bioresorbable and non-bioresorbable medical polymers.Part one provides a review of the types and properties of bioresorbable medical polymers. The effect of molecular structure on properties is discussed, along with the processing of bioresorbable and other polymers for medical applications. Transport phenomena and the degradation of bioresorbable medical polymers are reviewed, before an exploration of synthetic bioresorbable polymers and their use in orthopaedic tissue regeneration. Part two goes on to explore the durability and reliability of non-bioresorbable medical polymers, and wear processes in polymer implants and ageing processes of biomedical polymers in the body are discussed in depth, before an investigation into manufacturing defects and the failure of synthetic polymeric medical devices.With its distinguished editors and international team of expert contributors, Durability and reliability of medical polymers is an essential tool for all materials scientists, researchers and engineers involved in the design, development and application of medical polymers, whilst also providing a helpful overview of the subject for biologists, chemist and clinicians.

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    Woodhead Publishing Series in Biomaterials

    Part I: Types and properties of bioresorbable medicalpolymers

    Chapter 1: Types of bioresorbable polymers for medical applications

    Abstract:

    1.1 Introduction

    1.2 Aliphatic polyesters

    1.3 Polyanhydrides

    1.4 Poly(ortho esters)

    1.5 Polyphosphazenes

    1.6 Poly(amino acids) and 'pseudo' poly(amino acids)

    1.7 Polyalkylcyanoacrylates

    1.8 Poly(propylene fumarate) (PPF), poloxamers, poly(p-dioxanone) (PPDO), polyvinyl alcohol (PVA)

    Chapter 2: The effect of molecular structure on the properties of biomedical polymers

    Abstract:

    2.1 Introduction: the molecular structure of polymers

    2.2 Molecular weight and polymer properties

    2.3 Macromolecular conformation, crystallisation and polymer properties

    2.4 The effect of the amorphous state and glass transition temperature on polymer properties

    2.5 Biphasic systems: linear crystalline polymers and their properties

    Chapter 3: Processing of bioresorbable and other polymers for medical applications

    Abstract:

    3.1 Introduction

    3.2 Extrusion

    3.3 Mixing processes

    3.4 Molding processes

    3.5 Secondary shaping

    3.6 Calendering

    3.7 Coating

    3.8 Foaming

    3.9 Solvent casting

    3.10 Challenges in biopolymer processing

    3.11 Conclusions

    Chapter 4: Understanding transport phenomena and degradation of bioresorbable medical polymers

    Abstract:

    4.1 Introduction to transport phenomena in irreversible processes

    4.2 Introduction to mathematical modelling

    4.3 Conclusions and future trends

    Chapter 5: Synthetic bioresorbable polymers

    Abstract:

    5.1 Introduction

    5.2 Bioresorbable polymers

    5.3 Degradation of aliphatic polyesters

    5.4 Factors affecting aliphatic polymer degradation

    5.5 Processing and devices

    5.6 Conclusions

    Chapter 6: Using synthetic bioresorbable polymers for orthopedic tissue regeneration

    Abstract:

    6.1 Introduction

    6.2 Poly (?-hydroxy acids)

    6.3 Polylactones

    6.4 Polyanhydrides

    6.5 Fumarate-based polymers

    6.6 Hydrogels

    6.7 Future trends

    6.8 Conclusions

    Part II: Aspects of durability and reliability of non-bioresorbable medical polymers

    Chapter 7: Wear processes in polymer implants

    Abstract:

    7.1 Introduction

    7.2 Implants

    7.3 Wear processes and theory for polymer implants

    7.4 Polymers

    7.5 Wear debris in the body

    7.6 Future trends

    7.7 Sources of further information and advice

    Chapter 8: Ageing processes of biomedical polymers in the body

    Abstract:

    8.1 Introduction

    8.2 Principles of chemical and biochemical degradation and calcification

    8.3 Effect of natural ageing of medical polymers

    8.4 Principles of accelerated ageing

    8.5 Conclusions and summary

    8.6 Sources of further information and advice

    8.7 Acknowledgements

    Chapter 9: The failure of synthetic polymeric medical devices

    Abstract:

    9.1 Introduction

    9.2 Forensic methods

    9.3 Catheter failure

    9.4 Balloon catheters and angioplasty

    9.5 Breast implants

    9.6 Intraocular lenses

    9.7 Failure of Foley catheters

    9.8 Sutures

    9.9 Conclusions

    9.10 Acknowledgements

    Chapter 10: Manufacturing defects in polymeric medical devices

    Abstract:

    10.1 Introduction

    10.2 Polymer moulding

    10.3 Catheter systems

    10.4 Security cap for gas cylinders

    10.5 Breathing tube failures

    10.6 A failed crutch

    10.7 Cracked medical tubing

    10.8 Conclusions

    10.9 Acknowledgements

    Index

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