Carbohydrates in Drug Discovery and Development by Tiwari, Vinod K.;

Synthesis and Application

10% KEDVEZMÉNY?
A kedvezmény csak az 'Értesítés a kedvenc témákról' hírlevelünk címzettjeinek rendeléseire érvényes.

Kiadói listaár EUR 197.00
Az ár azért becsült, mert a rendelés pillanatában nem lehet pontosan tudni, hogy a beérkezéskor milyen lesz a forint árfolyama az adott termék eredeti devizájához képest. Ha a forint romlana, kissé többet, ha javulna, kissé kevesebbet kell majd fizetnie.

81 705 Ft (77 815 Ft + 5% áfa)
Kedvezmény(ek) 10% (cc. 8 171 Ft off)
Kedvezményes ár 73 535 Ft (70 034 Ft + 5% áfa)

81 705 Ft

Beszerezhetőség

Megrendelésre a kiadó utánnyomja a könyvet. Rendelhető, de a szokásosnál kicsit lassabban érkezik meg.

A termék adatai:

Kiadó Elsevier Science
Megjelenés dátuma 2020. augusztus 1.

ISBN 9780128166758
Kötéstípus Puhakötés
Terjedelem714 oldal
Méret 228x152 mm
Súly 1130 g
Nyelv angol

Kategóriák

Szerves kémia

Hosszú leírás:

Carbohydrates in Drug Discovery and Development: Synthesis and Applications examines recent and notable developments in the synthesis, biology, therapeutic, and biomedical applications of carbohydrates, which is considered to be a highly promising area of research in the field of medicinal chemistry. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell surface recognition formulate the carbohydrate systems to be an exceedingly considerable scaffold for the development of new chemical entities of pharmacological importance. In addition to their easy accessibility, high functionality and chiralpool characteristics are the few additional fascinating structural features of carbohydrates, which further enhance their utilities and thus they have been able to attract chemists and biologists toward harnessing these properties for the past several decades.This book covers an advanced aspect of carbohydrate-based molecular scaffolding, starting with a general introduction followed by a detailed discussion about the impact of diverse carbohydrate-containing molecules of great therapeutic values and their impact on drug discovery and development. The topics covered in this book include the significance of heparin mimetics as the possible tools for the modulation of biology and therapy, chemistry and bioactivities of C-glycosylated compounds, inositols, iminosugars, KDO, sialic acids, glycohybrids, macrocycles, plant oligosaccharides, anti-bacterial and anti-cancer vaccines, antibiotics, and more.

Több

Tartalomjegyzék:

1. Recent trends and challenges on carbohydrate-based molecular scaffolding: general consideration toward impact of carbohydrates in drug discovery and development
2. Heparin mimetics as tools for modulation of biology and therapy
3. Bioactive C-glycosides inspired from natural products toward therapeutics
4. 3-Deoxy-d-manno-oct-2-ulosonic acid (Kdo) derivatives in antibacterial drug discovery
5. Sialic acid-containing molecules in drug discovery and development
6. Glycan microarray: Toward drug discovery and development
7. Recent developments in the synthesis of biologically relevant Iinositol derivatives
8. Iminosugars in medicinal chemistry
9. Carbohydrate-protein interactions: Enhancing multivalency effects through statistical rebinding
10. Carbo-click in drug discovery and development: Opportunity and challenges
11. Glycohybrids molecule in medicinal chemistry: Present status and future prospective
12. Biologically active carbohydrate-containing macrocycles
13. Carbohydrate-based antibiotics: Opportunities and challenges
14. Carbohydrate-based anti-bacterial and anti-cancer vaccines
15. Opportunity of plant oligosaccharides and polysaccharides in drug development
16. N-acetylgalactosamine (GalNAc)-conjugates: Delivering oligonucleotide drugs to the liver