Tumor Lymphocyte Infiltrate (TILs):
association with clinicopathological factors and prognostic value in adjuvant breast cancer
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18 207 Ft
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Product details:
- Publisher Our Knowledge Publishing
- Date of Publication 1 January 2022
- Number of Volumes Großformatiges Paperback. Klappenbroschur
- ISBN 9786205229385
- Binding Paperback
- No. of pages52 pages
- Size 220x150 mm
- Language English 225
Categories
Long description:
Introduction: Tumor infiltration by lymphocytes (TILs) is a prognostic factor. The aim of our study is to determine the correlation between tumor lymphocyte infiltration and various clinicopathological factors and to evaluate its impact on recurrence-free survival. Patients and methods: This is a monocentric and retrospective study of 93 consecutive patients treated in the adjuvant setting for non-metastatic breast cancer at the Hôpital Militaire Principal d'Instruction de Tunis (HMPIT) between 2011 and 2018. Lymphocyte infiltration was quantified for each and survival times were calculated by the Kaplan-Meier method.Results: TILs were significantly associated with negative hormone receptor status, young age, high proliferation index and high SBR grades (2-3) . For the survival of the cohort, the importance of TILs was not statistically related to SRH and OS but there was a trend towards better survival with high proportions of TILs. Conclusion: . High proportions of TILs seem to have a positive impact on survival.
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