The Pharmacology of Alcohol and Alcohol Dependence
Series: Alcohol and Alcoholism;
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Product details:
- Publisher OUP USA
- Date of Publication 23 May 1996
- ISBN 9780195100945
- Binding Hardback
- No. of pages536 pages
- Size 241x176x29 mm
- Weight 860 g
- Language English
- Illustrations line figures 0
Categories
Short description:
This reference work covers the general pharmacology and neuropharmacology of alcohol as well as the pharmacological mechanisms underlying alcoholism.
MoreLong description:
This is a comprehensive review of the pharmacological effects of alcohol and the mechanisms underlying the pathogenesis of alcoholism. The book draws on general pharmacology, neuropharmacology, and alcohol studies to explore its theme. The second volume in the ALCOHOL AND ALCOHOLISM series, it focuses on the pharmacologic mechanisms underlying the development of alcoholism. The first section on basic pharmacology is concerned with those aspects that are common to all of alcohol's effects. These include pharmacokinetics, general metabolism, and cross-tolerance. The second section on neuropharmacology describes the effects of alcohol on various brain functions, including circulation and metabolism. The third section provides an in-depth review of the neurobiology of physical dependence, withdrawal, and physiological tolerance. The book as a whole gives a comprehensive and authoritative picture of the complex pharmacologic actions of alcohol, particularly on the nervous system. For clinicians and researchers in the field of alcohol and alcoholism, it will serve as a fundamental reference.
MoreTable of Contents:
The Pharmacology of Alcohol Dependence
Part I: General Pharmacology of Alcohol
Pharmacokinetics of Ethanol: Absorption, Distribution and Elimination
Metabolism of Ethanol, Acetaldehyde and Condensation Products
Cross-Tolerance: Theoretical and Experimental Issues
Part II: Neuropharmacology of Alcohol
Effects of Alcohol on Brain Circulation
Alcohol, Alcoholism, and the Autonomic Nervous System: A Critical Account
Part III: Neuropharmacology of Physical Dependence, Withdrawal, and Physiological Tolerance
Effects of Alcohol on Neuronal Membranes
Effect of Ethanol on Voltage-Gated Ion Channels
Effect of Alcohol n Neurotransmitters and their Receptors and Enzymes
Pharmacological Effects in the Development of Physiological Tolerance and Physical Dependence
Neurobiological Substrates for the Anti-Anxiety Effects of Ethanol