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    The Mouse in Biomedical Research: Diseases

    The Mouse in Biomedical Research

    Diseases

    Series: American College of Laboratory Animal Medicine; 2;

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      • Publisher's listprice EUR 480.00
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    Product details:

    • Edition number 2
    • Publisher Elsevier Science
    • Date of Publication 22 January 2007

    • ISBN 9780123694546
    • Binding Unidentified
    • No. of pages2192 pages
    • Size 279x216 mm
    • Weight 6950 g
    • Language English
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    Long description:

    In no other species of animal has such a wealth of experimental data been utilized for scientific pursuits. Now in its Second Edition, this Four Volume Set is dedicated to the understanding of the mouse and its role in scientific research. This valuable compendium serves as a standard reference source of information for students embarking on scientific careers, specialists in laboratory animal science, technicians in both animal care and research, and the broad scientific community. This set is also sold individually and covers History, Wild Mice, and Genetics; Diseases; Normative Biology, Husbandry, and Models; and Immunology.Volume 1: History, Wild Mice, and GeneticsKEY FEATURES:. A primer for scientists new to the field of mouse research. Information about the history, biology and genomics of the laboratory mouse (Mus musculus). Mouse origins and relationships covered in chapters on history, evolutionary taxonomy and wild mice. Mouse genetics and genomics discussed in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular organization of the mouse genome. Use of the mouse as a model system for basic biomedical research described in chapters on chemical mutagenesis, gene trapping, pharmacogenetics and embryo manipulationVolume 2: DiseasesKEY FEATURES:. New format by discussing specific disease causing microorganisms versus the format used in the first edition which discussed infectious diseases affecting specific organs and tissues. Consists of 26 chapters subdivided into RNA viruses and DNA viruses, mycotic, and parasitic infections. . Provides updates on pathogenesis, epidemiology and prevention of previously recognized murine pathogens. Offers information on newly recognized disease-causing organisms: mouse parvovirus, cilia associated respiratory bacilli and Helicobacter Volume 3: Normative Biology, Husbandry, and ModelsKEY FEATURES:. Encompasses 23 chapters with a broad overview on the laboratory mouse's normative biology, husbandry, and its use as a model in biomedical research. . Includes chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry.. Discusses management, nutrition, gnotobiotics and disease surveillance. Provides analysis of the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases Volume 4: ImmunologyKEY FEATURES:. A complete new addition to this series, dedicated to mouse immunology including both the innate and adaptive immune systems. Based on the mouse as a choice model when studying immunity in man-arguably more is known about the immune system in mice than any other species except man. Chapters illustrate the power of genetic engineering in dissecting each component of the immune response from the development of lymphoid tissues to signal transduction pathways in activated cells

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    Table of Contents:

    Volume I History, Wild Mice, and Genetics

    1. Building a Better Mouse: One Hundred Years of Genetics and Biology
    Herbert C. Morse III

    2. Systematics of the genus Mus
    Priscilla K. Tucker

    3. The Secret World of Wild Mice
    Grant R. Singleton and Charles J. Krebs

    4. Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types
    Melissa L. Berry and Carol Cutler Linder

    5. Mouse Strain and Genetic Nomenclature: an Abbreviated Guide
    Janan T. Eppig

    6. The Mouse Genome
    Mark D. Adams

    7. Gene Mapping
    Muriel T. Davisson

    8. Genetic Monitoring
    Richard R. Fox, Michael V. Wiles, and Petko M. Petkov

    9. Cytogenetics
    Muriel T. Davisson and Mary Ann Handel

    10. Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man
    M.H. Kaufman

    11. Gamete and Embryo Manipulation
    K.C. Kent Lloyd

    12. Chemical Mutagenesis in Mice
    Martin Hrabï¿1⁄2 de Angelis, Dian Michel, Sibylle Wagner, Sonja Becker and Johannes Beckers

    13. Gene-Specific Mutagenesis
    K.C. Kent Lloyd

    14. Gene Transfer Studies Using Mouse Models
    Robert G. Pergolizzi and Ronald G. Crystal

    15. Mouse and Human Pluripotent Stem Cells
    Leslie F. Lock

    16. Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics
    Lucia F. Jorge-Nebert, Sandrine Derkenne and Daniel W. Nebert


    Volume II Diseases

    Viral Diseases

    DNA Viruses

    1. Mouse Cytomegalovirus and other Herpesviruses
    Geoffrey R. Shellam, Alec J. Redwood, Lee M. Smith and Shelley Gorman

    2. Mouse Adenoviruses
    Katherine R. Spindler, Martin L. Moore, Angela N. Cauthen

    3. Mousepox
    R. Mark L. Buller and Frank Fenner

    4. Parvoviruses
    Robert O. Jacoby and Lisa Ball-Goodrich

    5. Polyoma Viruses
    Thomas L. Benjamin


    RNA Viruses

    6. Mouse Hepatitis Virus
    Stephen W. Barthold and Abigail L. Smith

    7. Lymphocytic Choriomeningitis Virus
    Stephen W. Barthold and Abigail L. Smith

    8. Lactate Dehydrogenase-Elevating Virus
    Jean-Paul Coutelier and Margo A. Brinton

    9. Reoviridae
    Richard L. Ward, Monica M. McNeal, Mary B. Faron and Anthony L. Farone

    10. Retroelements in the Mouse
    Herbert C. Morse III

    11. Sendai Virus and Pneumonia Virus of Mice (PVM)
    David G. Brownstein

    12. Cardioviruses: Encephalomyocarditis Virus and Theiler's Mouse Encephalomyelitis Virus
    Howard L. Lipton, A.S. Manoj Kumar, and Shannon Hertzler


    Bacterial Diseases

    13. Chlamydial Diseases
    Robert G. Rank

    14. Clostridial Species
    Kimberly S. Waggie

    15. Enterobacteriaceae, Pseudomonas aeruginosa, and Streptobacillus moniliformis
    Hilda Holcombe and David B. Schauer

    16. Aerobic Gram-positive Organisms
    Cynthia Besch-Williford and Craig L. Franklin

    17. Helicobacter Infections in Mice
    James G. Fox and Mark T. Whary

    18. Mycoplasma pulmonis, Other Mouse Mycoplasmas, and Cilia-Associated Respiratory Bacillus
    Trenton R. Schoeb

    19. Pasteurellaceae
    Werner Nicklas


    Mycotic and Parasitic Diseases

    20. Fungal Diseases in Laboratory Mice
    Virginia L. Godfrey

    21. Protozoa
    Katherine Wasson

    22. Helminth Parasites of Laboratory Mice
    Kathleen R. Pritchett

    23. Anthropods
    David G. Baker


    Miscellaneous Diseases

    24. The Tumor Pathology of Genetically Engineered Mice: A New Approach to Molecular Pathology
    Robert D. Cardiff, Robert J. Munn, and Jose J. Galvez

    25. Spontaneous Diseases in Commonly Used Mouse Strains
    Cory Brayton

    26. Zoonoses and Other Human Health Hazards
    Christian E. Newcomer and James G. Fox


    Volume III Normative Biology, Husbandry, and Models

    Normative Biology

    1. Gross Anatomy
    Vladimï¿1⁄2r Komï¿1⁄2rek

    2. Mouse Physiology
    Robert F. Hoyt, Jr., James V. Hawkins, Mark B. St Claire and Mary B. Kennett

    3. Reproductive Biology of the Laboratory Mouse
    Kate Pritchett and Robert Taft

    4. Endocrinology: Bone as a target tissue for hormonal regulation
    Krista M. Delahunty and Wesley G. Beamer

    5. Hematology of the Laboratory Mouse
    Nancy E. Everds

    6. Clinical Chemistry of the Laboratory Mouse
    Fred W. Quimby and Richard H. Luong


    Management, Techniques, and Husbandry

    7. Gnotobiotics
    Richard J. Rahija

    8. Management and Design: Breeding Facilities
    William J. White

    9. Design and Management of Research Facilities for Mice
    Neil S. Lipman

    10. Nutrition
    Graham Tobin, Karla A. Stevens and Robert J. Russell

    11. Health Delivery and Quality Assurance Programs for Mice
    Diane J. Gaertner, Glen Otto and Margaret Batchelder

    12. Environmental and Equipment Monitoring
    J. David Small and Rick Deitrich

    13. Biomethodology and Surgical Techniques
    Alison M. Hayward, Laura B. Lemke, Erin C. Bridgeford, Elizabeth J. Theve, Courtnye N. Jackson, Terrie L. Cunliffe-Beamer, Robert P. Marini

    14. In Vivo Whole-Body Imaging of the Laboratory Mouse
    Simon R. Cherry


    Use of Mice in Biomedical Research

    15. Behavioral Testing
    Douglas Wahlsten and John C. Crabbe

    16. Cardiovascular Disease: Mouse Models of Atherosclerosis
    Nobuyo Maeda, Raymond C. Givens and Robert L. Reddick

    17. Convulsive Disorders
    Mariana T. Todorova and Thomas N. Seyfried

    18. Eye Research
    Richard S. Smith, Patsy M. Nishina, John P. Sundberg, Johann Zwaan, and Simon W.M. John

    19. Genetic Analysis of Rodent Obesity and Diabetes
    Sally Chiu, Janis S. Fisler, and Craig H. Warden

    20. Mouse Models in Aging Research
    Kevin Flurkey, Joanne M. Currer, and D.E. Harrison

    21. Mouse Models of Inherited Human Neurodegenerative Disease
    Karl Herrup

    22. Mouse Skin Ectodermal Organs
    Maksim V. Plikus, John P. Sundberg, and Cheng-Ming Chuong

    23. Quality Control Testing of Biologicals
    William R. Shek


    Volume IV Immunology

    Molecular and Cellular Immunology of the Mouse: An Overview
    Fred W. Quimby and David D. Chaplin

    1. The Molecular Basis of Lymphoid Architecture in the Mouse
    Carola G. Vinuesa and Matthew C. Cook

    2. The Biology of Toll-like Receptors in Mice
    Osamu Takeuchi and Shizuo Akira

    3. Genomic Organization of the Mouse Major Histocompatibility Complex
    Attila Kumï¿1⁄2novics

    4. Some Biological Features of Dendritic Cells in the Mouse
    Kang Liu, Anna Charalambous and Ralph M. Steinman

    5. Mouse Models Revealed the Mechanisms for Somatic Hypermutation and Class Switch
    Recombination of Immunoglobulin Genes
    Maria D. Iglesias-Ussel, Ziqiang Li, and Matthew D. Scharff

    6. Mouse Natural Killer Cells: Function and Activation
    Francesco Colucci

    7. Cytokine-activated JAK-STAT Signaling in the Mouse Immune System
    Bin Liu and Ke Shuai

    8. Signal Transduction Events Regulating Integrin Function and T Cell Migration in the Mouse
    Lakshmi R. Nagarajan and Yoji Shimizu

    9. Mouse Models of Negative Selection
    Troy A. Baldwin, Timothy K. Starr and Kristin A. Hogquist

    10. Peripheral Tolerance of T Cells in the Mouse
    Vigo Heissmeyer, Bogdan Tanasa, and Anjana Rao

    11. The Genetics of Mouse Models of Systemic Lupus
    Srividya Subramanian and Edward K. Wakeland

    12. Inhibitory Receptors and Autoimmunity in the Mouse
    Menna R. Clatworthy and Kenneth G.C. Smith

    13. Mouse Models of Immunodeficiency
    B. Anne Croy, James P. Di Santo, Marcus Manz, and Richard B. Bankert

    14. Mouse Models to Study the Pathogenesis of Allergic Asthma
    Chad E. Green, Nicholas J. Kenyon, Scott I. Simon, and Fu-Tong Liu

    15. The Mouse Trap: How Well Do Mice Model Human Immunology?
    Javier Mestas and Christopher C.W. Hughes

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