Product details:
| ISBN13: | 9780323918428 |
| ISBN10: | 0323918425 |
| Binding: | Paperback |
| No. of pages: | 200 pages |
| Size: | 276x216 mm |
| Weight: | 450 g |
| Language: | English |
| 700 |
Category:
The Chemistry of Hyperpolarized Magnetic Resonance Probes
Publisher: Academic Press
Date of Publication: 17 May 2024
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Long description:
The Chemistry of Hyperpolarized Magnetic Resonance Probes, Volume Seven focuses on the chemical aspects of hyperpolarized NMR/MRI technology, with synthesis and characterizations of labeled compounds discussed from a practical point-of-view. A brief overview of the various hyperpolarization techniques are given, with the optimization of hyperpolarization conditions and the determination of critical parameters such as polarization level and T1 relaxation values described. A practical guide on the in vivo applications of hyperpolarized compounds in small animals is also included.
- Helps readers understand the structural features that determine the properties of HP-probes, such as chemical shift and relaxation times
- Aids readers in selecting stable isotope labeled probes for hyperpolarized NMR/MRI applications
- Teachers readers how to use the most appropriate synthetic methodology for the labeled probes
- Covers how to find the most suitable polarization technique (DNP, PHIP etc.) for the probe
Table of Contents:
1. Hyperpolarized tracer design, synthesis and characterization
2. Optimization of hyperpolarized NMR signals in dissolution dynamic nuclear polarization
3. The chemistry of parahydrogen induced polarization (PHIP)
4. Beyond 13C-pyruvate: Biomedical applications with alternate hyperpolarized probes
5. Technical Considerations of MRI methods for validating DNP probes in small animals
2. Optimization of hyperpolarized NMR signals in dissolution dynamic nuclear polarization
3. The chemistry of parahydrogen induced polarization (PHIP)
4. Beyond 13C-pyruvate: Biomedical applications with alternate hyperpolarized probes
5. Technical Considerations of MRI methods for validating DNP probes in small animals
