The Biological Chemistry of the Elements
The Inorganic Chemistry of Life
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Product details:
- Edition number 2
- Publisher OUP Oxford
- Date of Publication 16 August 2001
- ISBN 9780198508489
- Binding Paperback
- No. of pages600 pages
- Size 247x189x32 mm
- Weight 1321 g
- Language English
- Illustrations numerous line figures 0
Categories
Short description:
This text describes the functional role of the twenty inorganic elements essential to life in living organisms.
MoreLong description:
Twenty inorganic elements, mostly metal ions, are consistently found in living systems and are essential for living systems to function correctly. The aim of this text is to discuss, describe, and explain the functional relevance of those elements: the reasons for their selection; the processes of their uptake, transport and final localization in cells; the regulation of these processes; and the interactive network of their reactions that connects the in vivo inorganic elements to the environment and to the genome.
The first seven chapters describe the physical, chemical, and biological principles of the involvement of the elements in cellular activity, stressing how inorganic and organic chemicals react differently together in different compartments. The next twelve chapters describe the uses of the individual essential inoranic elements and a section on the genetic control of each element is included. The final chapter discusses how the interaction of genes, proteins, small molecules, and inorganic elements plays an important role in evolution and the speciation of organisms.
The second edition of 'The Biological Chemistry of The Elements' has been thoroughly revised in content and style. The main additions to the first edition concern the discussion of the links to the genome of the uptake and transfer of inorganic elements and the regulation of homeostasis, the functional co-operative activities of the elements, the interaction with the environment, and the evolution of usage. Recent structural and mechanistic knowledge of many biomolecules and organelles are also included.
Like the higly praised first edition, this text will be the bible of bioinorganic chemistry.
Review from previous edition "Rich and refreshing...in addition to being a general resource, this engaging book provides an excellent text for an advanced course and should have much to teach both students and teachers." Nature
Table of Contents:
The chemical elements in biology
The principles of the uptake and chemical speciation of the elements in biology
Physical separations of elements: compartments and zones in biology
Kinetic considerations of chemiscal reactions, catalysis, and control
Energy in biological systems and hydrogen biochemistry
The role of biological macromolecules and polymers
The functional value of the chemical elements in biological systems
Sodium, potassium, and chlorine: osmotic control, electrolytic equilibria, and currents
The biological chemistry of magnesium: phosphate metabolism
Calcium: controls and triggers
Zinc: Lewis acid catalysis and regulation
Non-haem iron: redox reactions and controls
Haen iron: coupled redox reactions
Manganese: dioxygen evolution and glycosylation
Copper: extracytoplasmic oxidases and matrix formation
Nickel and cobalt: remnants of early life
Molybdenum, tungsten, vanadium, and chromium
Phosphate, silica, and chloride: acid-base non-metals
Sulphur, selenium, and the halogens: redox non-metals
Integrated living systems of elements
