Stimuli-Responsive Biomaterials for Inflammatory Diseases by Ahmed, Mohammed Gulzar; Subramaniyan, Vetriselvan; Nag, Sagnik;

Short description:

This book reviews the use of stimuli-responsive biomaterials in the diagnosis, treatment, and management of inflammatory diseases. It begins by providing a foundational understanding of inflammatory diseases and presents fundamental principles of stimuli-responsive biomaterials. 

Long description:

This book reviews the use of stimuli-responsive biomaterials in the diagnosis, treatment, and management of inflammatory diseases. It begins by providing a foundational understanding of inflammatory diseases and presents fundamental principles of stimuli-responsive biomaterials. This book provides insights into the characteristics of ideal biomaterials and the chemical principles that enable stimuli-responsive drug delivery systems to function effectively. A detailed classification of these advanced materials is presented based on their responsive triggers, such as pH, temperature, light, and biological signals. The application of stimuli-responsive biomaterials in cancer therapeutics is discussed, as is their use in addressing autoimmune disorders, including lupus and rheumatoid arthritis, through targeted treatment strategies. The book also covers the innovative uses of these materials in managing inflammatory arthritis and various bone disorders, focusing on targeted drug delivery and improved patient outcomes. Further, it examines the potential of these smart materials in treating neuroinflammatory and neurological disorders, cardiovascular and cerebrovascular diseases, and in managing diabetes and obesity. The book highlights the development and application of injectable hydrogels that respond to various stimuli and presents the role of artificial intelligence and machine learning in the design of smart drug delivery systems. This book is intended for researchers working in biomedical engineering, drug delivery, and pharmaceutical sciences.

 Key Features:

• Provides an in-depth review of stimuli-responsive biomaterials and their applications in the diagnosis, treatment, and management of inflammatory diseases


• Presents classification of advanced biomaterials based on their responsive triggers, such as pH, temperature, light, and biological signals


• Highlights the use of stimuli-responsive biomaterials in cancer theranostics, autoimmune disorders, and targeted treatment strategies


• Emphasizes the development and application of injectable hydrogels and the integration of artificial intelligence in designing smart drug delivery systems


• Examines in-depth explanations of the chemical principles and mechanisms that enable stimuli-responsive drug delivery systems

Table of Contents:

1. Introduction to Inflammatory Diseases - Gaps and Prospects 2. Evolution and General Overview of Stimuli-Responsive Biomaterials 3.Ideal Biomaterials and Chemistry Underlying Stimuli-Responsive Drug Delivery 4. Classification and Categorization of Stimuli-Responsive Biomaterials 5. Stimuli-Responsive Biomaterials for Cancer Theranostics 6. Stimuli-Responsive Biomaterials for Inflammatory Arthritis and Other Bone Disorders 7.Stimuli-Responsive Biomaterials for Neuroinflammatory and Neurological Disorders 8. Stimuli-Responsive Biomaterials for Diabetes and Obesity Management 9. Stimuli-Responsive Biomaterials for Cardiovascular and Cerebrovascular Disorders (CCVDs) 10.Stimuli-Responsive Biomaterials for Inflammatory Autoimmune Disorders 11. Stimuli-Responsive Biomaterials for Chronic and Diabetic Inflammatory Wounds 12. Stimuli-Responsive Biomaterials for Imaging Modalities and Diagnosing Inflammatory Disorders 13. Smart Programmed Drug Delivery Systems: An Ode to AI and ML Technology 14. Recent Advances in 3D and 4D Bioprinting for Fabrication of Stimuli-Responsive Biomaterials