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  • RNA Viruses: A Practical Approach

    RNA Viruses by Cann, Alan;

    A Practical Approach

    Series: Practical Approach Series; 226;

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      • Publisher's listprice GBP 102.50
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    48 969 Ft

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    Out of print

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    Product details:

    • Publisher OUP Oxford
    • Date of Publication 4 May 2000

    • ISBN 9780199637164
    • Binding Paperback
    • No. of pages288 pages
    • Size 246x188x17 mm
    • Weight 635 g
    • Language English
    • Illustrations numerous figures, 13 halftones, 21 line drawings
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    Short description:

    RNA Viruses: A Practical Approach provides a broad treatment of the principles and practice of RNA virus research to ensure the widest possible audience. RNA Viruses: A Practical Approach will be of interest to all laboratories involved in virus culture, including both academic and industrial research groups and public health laboratories.

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    Long description:

    RNA Viruses: A Practical Approach is wide ranging in scope, from emerging technology such as reverse genetics and retrovirus vectors, to money saving tips - how to make your own silica particles for high efficiency RNA extraction and liposomes for cell transfection! Chapter one covers the fundamentals of investigating RNA virus genome structure at a molecular level. Chapters two and three describe techniques for mutagenesis of RNA genomes and analysis of
    transcription. Chapter four deals with RNA virus-encoded proteinases, an important aspect of the control of RNA virus gene expression. Chapter five considers retrovirus oncogenesis and chapter six analysis of RNA virus quasispecies. Chapter seven describes systems for investigation of in vitro replication of
    positive-stranded viruses and chapter eight the packaging of RNA virus genomes. In addition to the technical aspects of reverse genetics and retrovirus vectors, both of the final two chapters also consider ethical aspects of these new technologies.

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    Table of Contents:

    Investigation of RNA Virus Genome Structure
    Mutagenesis of RNA Virus Genomes
    Analysis of Transcriptional Control in RNA Virus Infections
    Analysis of RNA Virus-encoded Proteinases
    Detection and Analysis of Host Gene Targets for Oncogenic Retroviruses
    Analysis of RNA Virus Quasispecies
    In Vitro Replication of RNA Viruses
    Packaging of Segmented and non-segmented RNA Virus Genomes
    RNA Virus Reverse Genetics
    Development of RNA Virus Vectors for Gene Delivery

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